Evidence map›Paper›PMID 39888954›Full record

ArticlePLoS neglected tropical diseases2025

Rabies seropositive individuals, dogs, and healthcare professionals without prior vaccination in four Brazilian Indigenous communities.

Matheus Lopes Ribeiro, Camila Michele Appolinario, Bruna Letícia Devidé Ribeiro, João Henrique Farinhas, Fernando Rodrigo Doline, Gisely Toledo Barone, Juliana Amorim Conselheiro, Vamilton Alvarés Santarém, Leandro Meneguelli Biondo, Andrea Pires Dos Santos and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PLoS neglected tropical diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Matheus Lopes RibeiroDepartment of Animal Production and Preventive Veterinary Medicine, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.ORCID 0000-0002-4209-0986
Camila Michele AppolinarioDepartment of Animal Production and Preventive Veterinary Medicine, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
Bruna Letícia Devidé RibeiroDepartment of Animal Production and Preventive Veterinary Medicine, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.
João Henrique FarinhasGraduate College of Cell and Molecular Biology, Federal University of Paraná (UFPR), Curitiba, Paraná, Brazil.
Fernando Rodrigo DolineGraduate College of Cell and Molecular Biology, Federal University of Paraná (UFPR), Curitiba, Paraná, Brazil.
Gisely Toledo BaroneLaboratory of Diagnostics of Zoonosis and Vector-borne Diseases (LabZoo), Zoonosis Surveillance Division, Health Surveillance Coordination, Municipal Health Department, São Paulo, São Paulo, Brazil.
Juliana Amorim ConselheiroLaboratory of Diagnostics of Zoonosis and Vector-borne Diseases (LabZoo), Zoonosis Surveillance Division, Health Surveillance Coordination, Municipal Health Department, São Paulo, São Paulo, Brazil.
Vamilton Alvarés SantarémUniversity of Western São Paulo (UNOESTE), Presidente Prudente, São Paulo, Brazil.
Leandro Meneguelli BiondoInterdisciplinary Graduate Studies, University of British Columbia, Okanagan, Kelowna, British Columbia, Canada.
Andrea Pires Dos SantosPurdue University, West Lafayette, Indiana, United States of America.
Rogério GiuffridaUniversity of Western São Paulo (UNOESTE), Presidente Prudente, São Paulo, Brazil.
Louise Bach KmetiukPurdue University, West Lafayette, Indiana, United States of America.
Alexander Welker BiondoPurdue University, West Lafayette, Indiana, United States of America.
Jane MegidDepartment of Animal Production and Preventive Veterinary Medicine, São Paulo State University (UNESP), Botucatu, São Paulo, Brazil.ORCID 0000-0002-6540-7157

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indigenous communities are reportedly among the most vulnerable populations exposed to rabies worldwide. Accordingly, this study aimed to assess rabies serum titers from healthy Indigenous individuals, their dogs, and healthcare professionals of four Indigenous communities from São Paulo state, southeastern Brazil. Blood samples were collected, and an epidemiological questionnaire applied. The samples were processed by Fluorescent Antibody Virus Neutralization (FAVN) method. Overall, 35/299 (11.7%) individuals and 22/166 (13.2%) dogs without prior vaccination were seropositive. Furthermore, 4/18 (16.7%) healthcare professionals were seropositive, with only one reporting prior rabies vaccination. The lack of rabies titers in the remaining 14/18 (77.8%) healthcare professionals indicates no immune protection. Seropositivity was associated with being from the Kopenoty community (p = 0.026) and with owners reporting seeing their dogs in contact with bats (p = 0.022). In summary, these results should be considered as a warning for the risk of human-dog rabies exposure and infection, mainly due to bat contact.

Indexed as

Antibodies, ViralDog DiseasesHealth PersonnelRabiesRabies VaccinesRabies virusAdolescentAdultAnimalsBrazilChiropteraDogsFemaleHumansMaleMiddle AgedAntibodies, ViralRabies Vaccines

Identifiers

PMID39888954
PMCPMC11798433

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.