Evidence map›Paper›PMID 39888446›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Lifestyle recommendations and pelvic floor muscle training with Knack maneuver for post-prostatectomy urinary incontinence: a randomized controlled trial.

Ege Nur Atabey Gerlegiz, Türkan Akbayrak, Ceren Gürşen, Mustafa Sertaç Yazici, Naşide Mangir Bolat, Bülent Akdoğan, Gülbala Nakip, Serap Özgül

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04804839 (Comparison of the Effectiveness of Different Conservative Treatment Protocols in Individuals With Symptom of Postprostatectomy Urinary Incontinence), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04804839 nacompletednot on this map

Comparison of the Effectiveness of Different Conservative Treatment Protocols in Individuals With Symptom of Postprostatectomy Urinary Incontinence : a Randomized Controlled Trial

TypeinterventionalSponsorHacettepe UniversityRan2021 to 2022Enrolled72ConditionsUrinary Incontinence, Prostate Cancer, Urinary Incontinence,Stress, Urinary Incontinence Due to Urethral Sphincter IncompetenceArmsFirst research arm, Second research arm, Third research arm
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ege Nur Atabey GerlegizFaculty of Physical Therapy and Rehabilitation, Department of Fundamental Physiotherapy and Rehabilitation, Hacettepe University, Ankara, Turkey. egenuratabey@gmail.com.ORCID http://orcid.org/0009-0005-8295-8451
Türkan AkbayrakFaculty of Physical Therapy and Rehabilitation, Department of Fundamental Physiotherapy and Rehabilitation, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-5840-5252
Ceren GürşenFaculty of Physical Therapy and Rehabilitation, Department of Fundamental Physiotherapy and Rehabilitation, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-9204-8364
Mustafa Sertaç YaziciSchool of Medicine, Department of Urology, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-9616-3776
Naşide Mangir BolatSchool of Medicine, Department of Urology, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-3062-6480
Bülent AkdoğanSchool of Medicine, Department of Urology, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-6717-7677
Gülbala NakipFaculty of Physical Therapy and Rehabilitation, Department of Fundamental Physiotherapy and Rehabilitation, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0001-5331-786X
Serap ÖzgülFaculty of Physical Therapy and Rehabilitation, Department of Fundamental Physiotherapy and Rehabilitation, Hacettepe University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-2362-6773

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to investigate the additional effects of the Knack maneuver and comprehensive lifestyle recommendations to pelvic floor muscle training (PFMT) in individuals with post-prostatectomy urinary incontinence (PP-UI).

methodsSeventy-one individuals with symptom of PP-UI were included. Individuals were randomly assigned to study groups (Group I: PFMT + Knack + Comprehensive Lifestyle Recommendations, Group II: PFMT + Knack, Group III: PFMT alone). Assessments were performed at the baseline and at the end of the 8th week. The primary outcome was the subjective severity and impact of UI. Secondary outcomes were objective severity of UI, health-related quality of life (QoL) and patient global impression of severity and improvement. Descriptive and outcome measures were compared between study groups using the Kruskal-Wallis test. The Games-Howell post hoc test was also used to indicate which groups differ.

resultsA total of 66 patients were included in the final analysis. Per protocol analysis in all three groups showed significant improvements in all primary and secondary outcomes in eight weeks. The group of patients who had the PFMT + Knack + Comprehensive Lifestyle Recommendations had the greatest improvement in all outcome measures (p < 0.001). In addition, while PFMT + Knack showed superiority in terms of subjective UI severity and effect of UI on daily life, compared to PFMT alone (p < 0.001), there was no inter-group differences for objective UI severity and other subdomains of QoL (p > 0.05).

conclusionAdding comprehensive lifestyle recommendations and/or Knack maneuver to traditional PFMT is more effective in the management of post-prostatectomy UI in the short term. Further long-term follow-up studies should be planned to investigate compliance and response to these combined interventions. CLINICAL TRIAL REGISTRATION NUMBER: ClinicalTrials.gov NCT04804839. Date of registration: 03/17/2021.

Indexed as

Exercise TherapyLife StylePelvic FloorProstatectomyUrinary IncontinenceAgedHumansMaleMiddle AgedQuality of LifeSeverity of Illness IndexConservative treatmentFunctional pelvic floor muscle trainingKnack maneuverLifestyle changePhysiotherapyRadical prostatectomyUrinary Incontinence

Identifiers

PMID39888446
PMCPMC11785613

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.