Evidence map›Paper›PMID 39888430›Full record

ArticleParasitology research2025

Trends in insecticide resistance in natural populations of Culex quinquefasciatus and its impact on mosquito fitness in Dschang, West Cameroon.

Yacouba Poumachu, Michel Lontsi-Demano, Jehan Zeb, Joel Djoufounna, Borel Djiappi-Tchamen, Abeer Hashem, Reem Atalla Alajmi, Christelle Layelle Mochie, Herman Parfait Awono-Ambene, Christophe Antonio-Nkondjio and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasitology research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yacouba PoumachuInstitut for Research of Yaoundé, (IRY), Laboratory for Health Research of Central African Organization for Endemic Disease Control, P.O. Box 288, Yaounde, Cameroon. poumachuyacouba@gmail.com.
Michel Lontsi-DemanoVector Borne Diseases Laboratory of the Research Unit of Biology and Applied Ecology, (VBID- RUBEA), Department of Animal Biology, Faculty of Sciences of the University of Dschang, P.O. Box 067, Dschang, Cameroon.
Jehan ZebCentre for Immunology and Infection (C2i), Hong Kong Science and Technology Parks Corporation, Hong Kong SAR, China. zebjehan2012@gmail.com.
Joel DjoufounnaVector Borne Diseases Laboratory of the Research Unit of Biology and Applied Ecology, (VBID- RUBEA), Department of Animal Biology, Faculty of Sciences of the University of Dschang, P.O. Box 067, Dschang, Cameroon.
Borel Djiappi-TchamenInstitut for Research of Yaoundé, (IRY), Laboratory for Health Research of Central African Organization for Endemic Disease Control, P.O. Box 288, Yaounde, Cameroon.
Abeer HashemBotany and Microbiology Department, College of Sciences, King Saud University, P.O. Box. 2460, 11451, Riyadh, Saudi Arabia.
Reem Atalla AlajmiZoology Department, College of Sciences, King Saud University, P.O. Box. 2460, 11451, Riyadh, Saudi Arabia.
Christelle Layelle MochieVector Borne Diseases Laboratory of the Research Unit of Biology and Applied Ecology, (VBID- RUBEA), Department of Animal Biology, Faculty of Sciences of the University of Dschang, P.O. Box 067, Dschang, Cameroon.
Herman Parfait Awono-AmbeneInstitut for Research of Yaoundé, (IRY), Laboratory for Health Research of Central African Organization for Endemic Disease Control, P.O. Box 288, Yaounde, Cameroon.
Christophe Antonio-NkondjioInstitut for Research of Yaoundé, (IRY), Laboratory for Health Research of Central African Organization for Endemic Disease Control, P.O. Box 288, Yaounde, Cameroon.
Timoléon TchuinkamVector Borne Diseases Laboratory of the Research Unit of Biology and Applied Ecology, (VBID- RUBEA), Department of Animal Biology, Faculty of Sciences of the University of Dschang, P.O. Box 067, Dschang, Cameroon.
Elsayed Fathi Abd-AllahPlant Production Department, College of Food and Agricultural Sciences, King Saud University, P.O. Box. 2460, 11451, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific information about the dispersion of Culex quinquefasciatus from Dschang in western Cameroon is scarce, and evidence-based interventions are needed. Common use of larvicides and adulticides conduct to the development of vectors resistance which can lead to deep biological changes, including fitness costs. We assessed the profile of insecticide resistance in field populations of Cx. quiquefasciatus and its potential fitness cost in a lineage selected for deltamethrin and permethrin resistance in the laboratory for two generations. The resistance intensity of the Cx. quinquefasciatus population was moderated when the population was exposed to deltamethrin at 10 × . Preexposure to PBO led to the restoration of full susceptibility to both deltamethrin and permethrin. Compared with that of the control group, female fecundity rates, egg hatchability, and pupation rates were significantly lower in the insecticide exposed groups. Larval development time and adults emergence rates were comparable between insecticide-exposed groups and the control. Insecticide-exposed adults lived longer than control adults did. Our findings suggest that the mechanisms selected for pyrethroid resistance are associated with negative impacts on different life-trait parameters and support the hypothesis that insecticide resistance is related to a high fitness cost.

Indexed as

CulexGenetic FitnessInsecticide ResistanceInsecticidesMosquito VectorsAnimalsCameroonFemaleFertilityLarvaMaleNitrilesPermethrinPyrethrinsdecamethrinInsecticidesNitrilesPermethrinPyrethrinsCulicideFitnessInsecticide classesPBOVector control

Identifiers

PMID39888430
PMCPMC11785645

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.