Evidence map›Paper›PMID 39887897›Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Piezoelectric Biomaterial with Advanced Design for Tissue Infection Repair.

Siyuan Shang, Fuyuan Zheng, Wen Tan, Zhengyi Xing, Siyu Chen, Fuli Peng, Xiang Lv, Duan Wang, Xiangdong Zhu, Jiagang Wu and 3 more

Abstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. A Piezo-Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. MnOMaterials today. Bio · 2026
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Biopiezoelectric-based nanomaterials; a promising strategy in cancer therapy.Journal of experimental & clinical cancer research : CR · 2025
    Review
  17. Piezoelectric Biomaterial with Advanced Design for Tissue Infection Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Siyuan ShangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
Fuyuan ZhengSports Medicine Center, West China Hospital, Sichuan University, Chengdu, 610065, China.
Wen TanNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
Zhengyi XingNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
Siyu ChenNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
Fuli PengNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
Xiang LvCollege of Materials Science and Engineering, Sichuan University, Chengdu, 610065, China.
Duan WangSports Medicine Center, West China Hospital, Sichuan University, Chengdu, 610065, China.
Xiangdong ZhuNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
Jiagang WuCollege of Materials Science and Engineering, Sichuan University, Chengdu, 610065, China.
Zongke ZhouOrthopedic Research Institute and Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, 610041, China.
Xingdong ZhangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.
Xiao YangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, 610064, China.ORCID https://orcid.org/0000-0001-7248-8218

Funding

National Key Research and Development Program of China 2023YFB3813000National Key Research and Development Program of China 2023YFE0126900National Natural Science Foundation of China 32401108
6 · The paper itself

Abstract

Bacterial infection has become the most dangerous factor in tissue repair, which strongly affects the tissue regeneration efficiency and wellness of patients. Piezoelectric materials exhibit the outstanding advantage of producing electrons without external power supply. The ability of electron enrichment and reactive oxygen species generation through noninvasive stimulations enables piezoelectric materials the potential applications of antibacterial. Many studies have proved the feasibility of piezoelectric materials as a functional addition in antibacterial biomaterial. In fact, numerous piezoelectric materials with ingenious designs are reported to be effective in antibacterial processes. This review summarizes the antibacterial mechanisms of piezoelectric, illuminating their potential in combating bacteria. Recent advancement in the design and construction of piezoelectric biomaterial including defect engineering, heterojunction, synergy with metal and the composite scaffold configuration are thoroughly reviewed. Moreover, the applications and therapeutic effects of piezoelectric materials in common tissues with antibacterial requirements are introduced, such as orthopedics, dental, and wound healing. Finally, the development prospects and points deserving further exploration are listed. This review is expected to provide valuable insight into the relationship between antibacterial processes and piezoelectric materials, further inspiring constructive development in this emerging scientific discipline.

Indexed as

Anti-Bacterial AgentsBacterial InfectionsBiocompatible MaterialsAnimalsHumansTissue EngineeringWound HealingAnti-Bacterial AgentsBiocompatible Materialsantibacterialnanomaterialpiezocatalysispiezoelectricityreactive oxygen species

Identifiers

PMID39887897
PMCPMC11905007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.