Evidence map›Paper›PMID 39887894›Full record

ArticleAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2025

PR Interval as a Valuable Predictor of Tilt Table Test Results in Patients With Neurally Mediated Syncope.

Mohammad Hossein Nikoo, Roozbeh Narimani-Javid, Alireza Kamrava, Sasan Shafiei, Salma Nozhat, Hosein Fatemian, Ali Asadzadeh, Mehdi Motahari Moadab, Fatemeh Ghanbari, Alireza Arzhangzadeh

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Article in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohammad Hossein NikooNon-Communicable Disease Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0001-8338-094X
Roozbeh Narimani-JavidResearch Center for Advanced Technologies in Cardiovascular Medicine, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-9134-8787
Alireza KamravaStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Sasan ShafieiDepartment of Cardiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-3350-3232
Salma NozhatDepartment of Cardiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0009-0008-1404-4123
Hosein FatemianDepartment of Cardiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0001-5239-1582
Ali AsadzadehDepartment of Cardiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0009-0001-3114-079X
Mehdi Motahari MoadabDepartment of Cardiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0009-0007-3447-1563
Fatemeh GhanbariStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0001-6117-8660
Alireza ArzhangzadehDepartment of Cardiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-7466-7487

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeurally mediated syncope (NMS) is the primary cause of temporary and self-limiting loss of consciousness. The tilt table test (TTT) has been consistently employed as a supplementary diagnostic tool for syncope evaluation. However, TTT requires specialized equipment, which is lacking in several emergency room and clinic environments. We hypothesized that patients susceptible to NMS may have higher parasympathetic tone. Thus, this study investigates the correlation between PR interval and Herat rate variability parameters as indicators of parasympathetic tone and TTT results.

methodsWe included 213 patients referred to our cardiology clinic with an impression of NMS in 2022 and 2023. Data was retrospectively collected from 24-h ambulatory electrocardiographic monitoring recordings, TTT results, and patients' history and physical examination records.

resultsThe analysis of the PR interval revealed a mean duration of 155 ms (95% CI: 148.61, 161.39) in negative TTT patients and 164.21 ms (95% CI: 158.44, 169.97) in positive TTT patients, indicating a statistically significant difference between two groups (p = 0.035). We also found that patients with a PR interval duration exceeding 160 ms demonstrated a significantly higher prevalence of positive TTT compared to those with a PR interval duration of less than 160 ms (p < 0.001, OR: 3.911, 95% CI: 2.143, 7.140).

conclusionsOur study suggests a PR interval longer than 160 milliseconds as a valuable tool for predicting TTT results and identifying patients at higher risk of NMS.

Indexed as

ElectrocardiographyElectrocardiography, AmbulatorySyncopeSyncope, VasovagalTilt-Table TestAdultAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective Studiesambulatory electrocardiographic monitoringneurally mediated syncopePR intervaltilt‐table testvasovagal syncope

Identifiers

PMID39887894
PMCPMC11783229

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.