Evidence map›Paper›PMID 39887871›Full record

ArticlePM & R : the journal of injury, function, and rehabilitation2025

The Multilevel Limb-loss and Preservation Rehabilitation Continuum model (MLPRC): An evidence-based implementation model integrating multiple perspectives to improve outcomes for people facing limb loss.

Prateek Grover, Elvin Geng, Rachel G Tabak

Abstract read
In one paragraph

Article in PM & R : the journal of injury, function, and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. An introduction to implementation science in rehabilitation medicine.PM & R : the journal of injury, function, and rehabilitation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Prateek GroverPenn State Hershey Medical Center and Penn State College of Medicine, Hershey, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-1367-8438
Elvin GengWashington University in St. Louis, St. Louis, Missouri, USA.
Rachel G TabakWashington University in St. Louis, St. Louis, Missouri, USA.ORCID https://orcid.org/0000-0003-2967-3906

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Center for Diabetes Translation Research P30DK092950 · NIDDK · WASHINGTON UNIVERSITY · PI Ross C Brownson, Debra Haire-Joshu · 2011 to 2026
$11.7M
NCATS NIH HHS UL1 TR002345NIDDK NIH HHS P30 DK092950NIH CTSA UL1TR002345
6 · The paper itself

Abstract

backgroundThe patient journey from threatened to actual limb loss, subsequent rehabilitation, and limb preservation through the health system is complicated and prone to delays, attrition, and inequities. A shared multi(socioecological)-level conceptualization of this journey among the multiple stakeholders is the first step for systematically improving limb care through identification of bottlenecks and gaps, contributory factors, and responsive interventions and implementation strategies.

objectiveTo meet this knowledge gap by presenting a novel implementation model, the Multilevel Limb-loss and Preservation Rehabilitation Continuum (MLPRC), that can be used to develop multilevel applications.

methodsMLPRC was developed in three overlapping steps: (1) design of the patient journey through the health system (horizontal element), (2) addition of multilevel perspectives along the journey (vertical element), and (3) implementation facilitation by incorporating implementation model constructs (concentric cells element).

resultsMLPRC is an implementation model for limb loss and preservation with three concentric cells: inner context cell (horizontal time-ordered patient journey at patient level, based on phases of amputation rehabilitation and patient journey concepts, and corresponding care delivery at provider/organization-level, based on the continuum of care and lower limb loss rehabilitation continuum concepts, on the journey timeline), less influenceable outer context cell (community, system and policy level perspectives), and outermost implementation cell, based on Proctor Model of Implementation Research, that utilizes inner and outer context cells (concept derived from Exploration, Preparation, Implementation, Sustainment framework) information to define responsive metrics, interventions and implementation strategies. DISCUSSION: Examples of MLPRC use as a blueprint for multilevel applications include patient level (education and navigation instruments), provider level (integrated practice clinic, referral streams), organization level (limb care continuum programs), and community, system, and policy level (interdisciplinary organizational partnerships, data repositories).

conclusionMLPRC is among the first implementation model to present both a unified picture of the field of limb loss and preservation and a blueprint for multilevel applications.

Indexed as

Amputation, SurgicalAmputeesContinuity of Patient CareLimb SalvageHumans

Identifiers

PMID39887871
PMCPMC12659719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.