Evidence map›Paper›PMID 39887563›Full record

SynthesisAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Dual sensory impairment: Global prevalence, future projections, and its association with cognitive decline.

Brian Sheng Yep Yeo, Esther Yanxin Gao, Benjamin Kye Jyn Tan, Benedict Ding Chao Ong, Ryan Wei Yang Cho, Chee Yit Lim, Ryan Eyn Kidd Man, Eva K Fenwick, Preeti Gupta, Christopher Li-Hsian Chen and 6 more

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Dual sensory impairment: Global prevalence, future projections, and its association with cognitive decline.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Brian Sheng Yep YeoYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Esther Yanxin GaoYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Benjamin Kye Jyn TanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Benedict Ding Chao OngYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Ryan Wei Yang ChoYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Chee Yit LimYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Ryan Eyn Kidd ManSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Eva K FenwickSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Preeti GuptaSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.
Christopher Li-Hsian ChenMemory Aging and Cognition Centre, Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Samuel Teong Huang ChewYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Neville Wei Yang TeoDepartment of Otorhinolaryngology-Head and Neck Surgery, Singapore General Hospital, Singapore, Singapore.
Song Tar TohDepartment of Otorhinolaryngology-Head and Neck Surgery, Singapore General Hospital, Singapore, Singapore.
Jia Hui NgDepartment of Otorhinolaryngology-Head and Neck Surgery, Singapore General Hospital, Singapore, Singapore.
Vanessa Yee Jueen TanDepartment of Otorhinolaryngology-Head and Neck Surgery, Singapore General Hospital, Singapore, Singapore.
Ecosse L LamoureuxSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.ORCID https://orcid.org/0000-0001-8674-5705

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is rising public health concern surrounding dual sensory impairment (DSI), or comorbid hearing and vision impairments. Its global prevalence and the magnitude of its association with cognitive decline (CD) is unclear. Three databases were searched for epidemiological studies examining DSI prevalence or its association with CD. Independent reviewers selected studies, extracted data, and evaluated bias. Random-effects meta-analyses were performed. Projections were estimated using United Nations data. The population attributable fraction of DSI-associated CD was calculated. Among 43 studies with 5,246,796 participants, clinically assessed DSI prevalence was 5.50% (95% confidence interval [CI] = 2.88%-10.26%), with regional/ethnic/age variations. DSI prevalence is projected to increase by 27.2% from 2025 to 2050. Approximately 59.83% (95%CI = 41.03-76.12) of DSI patients had cognitive impairment. Baseline DSI was associated with incident CD (odds ratio [OR] = 1.72, 95%CI = 1.37-2.15). Globally, 3.81% (95%CI = 1.05-10.55) of incident CD may be attributed to DSI. DSI is globally prevalent, growing, and associated with CD, highlighting the need for better health policy and resource allocation. HIGHLIGHTS: The global prevalence of DSI is 5.50%, with geographical, ethnical and age variations. The prevalence of DSI rises with age and is projected to increase by 27.2% by 2050. Approximately 60% of individuals with DSI may have measurable cognitive impairment. DSI was associated with a 72% greater longitudinal risk of incident CD. Globally, 3.81% of CD cases may be attributable to DSI.

Indexed as

Cognitive DysfunctionHearing LossVision DisordersGlobal HealthHumansPrevalencecognitive declinecognitive impairmentdementiadual sensory impairmenthearing impairmentpublic healthvision impairment

Identifiers

PMID39887563
PMCPMC11851313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.