Evidence map›Paper›PMID 39887543›Full record

ArticleBioFactors (Oxford, England)

Vitamin D modulates the content of inflammatory microRNAs in extracellular vesicles from human adipocyte cells in inflammatory context.

Thomas Payet, Julien Astier, Lorrine Bournot, Flavie Sicard, Stéphane Robert, Romaric Lacroix, Martin Wabitsch, Jean-François Landrier, Lourdes Mounien

Abstract read
In one paragraph

Article in BioFactors (Oxford, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. 1α,25(OH)Nutrients · 2026
    Review
  2. Review
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas PayetAix Marseille University, INSERM, INRAE, C2VN, Marseille, France.
Julien AstierAix Marseille University, INSERM, INRAE, C2VN, Marseille, France.
Lorrine BournotAix Marseille University, INSERM, INRAE, C2VN, Marseille, France.
Flavie SicardAix Marseille University, INSERM, INRAE, C2VN, Marseille, France.
Stéphane RobertAix Marseille University, INSERM, INRAE, C2VN, Marseille, France.
Romaric LacroixAix Marseille University, INSERM, INRAE, C2VN, Marseille, France.
Martin WabitschDepartment of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.
Jean-François LandrierAix Marseille University, INSERM, INRAE, C2VN, Marseille, France.
Lourdes MounienAix Marseille University, INSERM, INRAE, C2VN, Marseille, France.ORCID https://orcid.org/0000-0002-9221-5783

Funding

Aix-Marseille UniversitéInstitut National de la Santé et de la Recherche MédicaleInstitut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
6 · The paper itself

Abstract

Inflammation of adipose tissue is a contributing factor to many chronic diseases associated with obesity. We previously showed that micronutrients such as vitamin D (VD) limited this metabolic inflammation by decreasing inflammatory markers expression including miR-155 (microRNA-155) or miR-146a in different in vitro and in vivo models. These miRNAs could be incorporated into extracellular vesicles (EVs) in order to modulate the activity of target cells. Nevertheless, the role of VD on the miRNAs contained in EVs from adipose tissue in inflammatory conditions remains unclear. In this study, we used a human model of SGBS (Simpson-Golabi-Behmel syndrome) adipocytes preincubated with 1,25(OH)

Indexed as

AdipocytesExtracellular VesiclesInflammationMicroRNAsVitamin DArrhythmias, CardiacChemokine CCL2Gene Expression RegulationGenetic Diseases, X-LinkedGigantismHeart Defects, CongenitalHumansIntellectual DisabilityTumor Necrosis Factor-alphaCCL2 protein, humanChemokine CCL2MicroRNAsMIRN146 microRNA, humanMIRN155 microRNA, humanTumor Necrosis Factor-alphaVitamin Dextracellular vesicleshuman adipocyteinflammationmicroRNAsVitamin D

Identifiers

PMID39887543
PMCPMC11779547

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.