Evidence map›Paper›PMID 39887017›Full record

ReviewNanomedicine (London, England)2025

Versatile nanomaterials used in combatting biofilm infections.

Chenlong Wang, S M Shatil Shahriar, Yajuan Su, Jingwei Xie

Abstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Biofilm-Responsive Nanoplatforms for Infected Wound Reconstruction.International journal of nanomedicine · 2026
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chenlong WangDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
S M Shatil ShahriarDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
Yajuan SuDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
Jingwei XieDepartment of Surgery-Transplant and Mary & Dick Holland Regenerative Medicine Program, College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.

Funding

Novel Janus-type Antimicrobial Dressings for the Treatment of Biofilms in Chronic WoundsR01GM138552 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI WANG, GUANGSHUN, XIE, JINGWEI · 2020 to 2023
$2.2M
NIGMS NIH HHS R01 GM138552
6 · The paper itself

Abstract

Microbial infections are a pressing global health issue, exacerbated by the rise of antibiotic-resistant bacteria due to widespread antibiotic overuse. This resistance diminishes the effectiveness of current treatments, intensifying the need for new antimicrobial agents and innovative drug delivery strategies. Nanotechnology presents promising solutions, leveraging the unique properties of nanomaterials such as tunable optical and electronic characteristics, nanoscale size, and high surface-to-volume ratios. These features enhance their effectiveness as innovative antimicrobial agents and versatile drug delivery systems. This minireview classifies antimicrobial nanomaterials into four categories based on their mechanisms of action: thermal generation, reactive oxygen species generation, gas generation, and nanocarrier systems such as liposomes, polymersomes, and metal-organic frameworks. Uniquely, this review integrates a comparative analysis of these mechanisms, highlighting their relative advantages, limitations, and applications across diverse microbial targets. Additionally, it identifies emerging trends in the field, providing a forward-looking perspective on how recent advancements in nanotechnology can be leveraged to address unmet clinical needs. Finally, this article discusses future directions and emerging opportunities in antimicrobial nanotechnology.

Indexed as

Anti-Bacterial AgentsBacterial InfectionsBiofilmsNanostructuresAnimalsBacteriaDrug Delivery SystemsHumansLiposomesNanotechnologyReactive Oxygen SpeciesAnti-Bacterial AgentsLiposomesReactive Oxygen Speciesantimicrobialgas generationnanocarriersNanomaterialROS generationthermal generation

Identifiers

PMID39887017
PMCPMC11875486

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.