Evidence map›Paper›PMID 39886719›Full record

ArticleCureus2024

Successful Diagnosis of a SMARCA4-Deficient Undifferentiated Tumor via Endobronchial Ultrasound-Guided Fine Needle Aspiration and Endobronchial Biopsies.

Luis F Meza, Mark Bowling, Soban Farooq, Bryan K Dunn

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Luis F MezaPulmonary and Critical Care Medicine, Brody School of Medicine, East Carolina University, Greenville, USA.
Mark BowlingPulmonary and Critical Care, Brody School of Medicine, East Carolina University, Greenville, USA.
Soban FarooqInternal Medicine and Pathology, Brody School of Medicine, East Carolina University, Greenville, USA.
Bryan K DunnPulmonary and Critical Care, Brody School of Medicine, East Carolina University, Greenville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is the third most prevalent cancer, following breast cancer in women and prostate cancer in men. However, it remains the leading cause of cancer-related mortality. As treatment options have advanced, the significance of accurate diagnosis has increased, enabling targeted and more personalized therapeutic treatments. SMARCA4-deficient thoracic tumors are a relatively new classification of mediastinal lung cancers that are known to be difficult to diagnose with conventional endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA). Newer modalities such as endobronchial ultrasound with cryobiopsy have emerged, and studies have indicated that they offer increased diagnostic yield when coupled with conventional EBUS-TBNA. Here, we present a case in which EBUS-TBNA alone produced sufficient tissue volume for immunohistochemistry at NeoGenomics (Fort Myers, FL), leading to a successful diagnosis.

Indexed as

bronchoscopyebus-tbnanon small cell lung cancersmarcasmarca deficient

Identifiers

PMID39886719
PMCPMC11780181

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.