Evidence map›Paper›PMID 39886675›Full record

ArticleJID innovations : skin science from molecules to population health2025

Wound Healing Splinting Devices for Faster Access and Use.

Andrew W Miller, Alexa R Anderson, Alejandra Suarez-Arnedo, Tatiana Segura

Abstract read
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew W MillerDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Alexa R AndersonDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Alejandra Suarez-ArnedoDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.
Tatiana SeguraDepartment of Biomedical Engineering, Duke University, Durham, North Carolina, USA.

Funding

Engineering Adaptive Immune Responses from Hydrogel Scaffolds to Promote Tissue RegenerationR01AI152568 · NIAID · DUKE UNIVERSITY · PI COLLIER, JOEL H, SEGURA, TATIANA · 2020 to 2024
$3.2M
NIAID NIH HHS R01 AI152568
6 · The paper itself

Abstract

With the goal of studying skin wound healing and testing new drug treatments to enhance wound healing in rodent models, there is a clear need for improved splinting techniques to increase surgical efficiency and support routine wound monitoring. Splinted wound healing models humanize wound healing in rodents to prevent contraction and instead heal through granulation tissue deposition, increasing the relevance to human wound healing. Current technologies require suturing and heavy wrapping, leading to splint failure and cumbersome monitoring of the wound. In this study, we developed a splint with resealable cap system that provides ease of access for wound inspection, therapeutic treatment delivery, and routine wound imaging without the need to unwrap and wrap the animal. Meanwhile, to overcome the challenges associated with suturing, we also developed adherent splints that can be applied to both hairless or haired mice with minimal wrapping. Both technologies are expected to improve and encourage the adoption of splinted wound healing models.

Indexed as

ImagingMethodsModelsTechniquesTools

Identifiers

PMID39886675
PMCPMC11780244

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.