Evidence map›Paper›PMID 39886560›Full record

ArticleFrontiers in neuroanatomy2025

Molecular characterization of chicken DA systems reveals that the avian personality gene,

Toshiyuki Fujita, Naoya Aoki, Chihiro Mori, Koichi J Homma, Shinji Yamaguchi

Abstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Toshiyuki FujitaDepartment of Biological Sciences, Faculty of Pharmaceutical Sciences, Teikyo University, Tokyo, Japan.
Naoya AokiDepartment of Molecular Biology, Faculty of Pharmaceutical Sciences, Teikyo University, Tokyo, Japan.
Chihiro MoriDepartment of Molecular Biology, Faculty of Pharmaceutical Sciences, Teikyo University, Tokyo, Japan.
Koichi J HommaDepartment of Molecular Biology, Faculty of Pharmaceutical Sciences, Teikyo University, Tokyo, Japan.
Shinji YamaguchiDepartment of Biological Sciences, Faculty of Pharmaceutical Sciences, Teikyo University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animal personalities are stable, context-dependent behavioral differences. Associations between the personality of birds and polymorphisms in the dopamine receptor D4 (DRD4) gene have been repeatedly observed. In mammals, our understanding of the role of the dopamine (DA) system in higher cognitive functions and psychiatric disorders is improving, and we are beginning to understand the relationship between the neural circuits modulating the DA system and personality traits. However, to understand the phylogenetic continuity of the neural basis of personality, it is necessary to clarify the neural circuits that process personality in other animals and compare them with those in mammals. In birds, the DA system is anatomically and molecularly similar to that in mammals; however, the function of DRD4 remains largely unknown. In this study, we used chicks as model birds to reveal the expression regions of the DA neuron-related markers

Indexed as

chickdopaminedopamine neurondopamine receptorDRD4mitral cellolfactory bulbpersonality gene

Identifiers

PMID39886560
PMCPMC11774857

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.