Evidence map›Paper›PMID 39886556›Full record

ArticleFrontiers in chemistry2024

Therapeutic potential of

Farouk Boudou, Amal Belakredar, Ahcen Keziz, Linda Aissani, Huda Alsaeedi, David Cronu, Mikhael Bechelany, Ahmed Barhoum

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Synthesis, characterization, andFrontiers in chemistry · 2026
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Farouk BoudouDepartment of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University of Sidi-Bel-Abbes, Sidi-Bel-Abbes, Algeria.
Amal BelakredarDepartment of Biotechnology, Faculty of Natural Sciences and Life, University of Mostaganem Abdelhamid Ibn Badis, Mostaganem, Algeria.
Ahcen KezizDepartment of Physics, Physics and Chemistry of Materials Laboratory, University of M'sila, M'sila, Algeria.
Linda AissaniMatter sciences Department, Abbes Laghrour- University of Khenchela, Khenchela, Algeria.
Huda AlsaeediDepartment of Chemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.
David CronuInstitut Européen des Membranes, IEM, UMR-5635, Univ Montpellier, ENSCM, CNRS, Montpellier, France.
Mikhael BechelanyInstitut Européen des Membranes, IEM, UMR-5635, Univ Montpellier, ENSCM, CNRS, Montpellier, France.
Ahmed BarhoumNanoStruc Research Group, Chemistry Department, Faculty of Science, Helwan University, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Monkeypox (Mpox) is a re-emerging zoonotic disease with limited therapeutic options, necessitating the exploration of novel antiviral agents. Aim: This study aimed to evaluate the therapeutic potential of Methodology: Phytochemical analysis, including HPLC, identified key Curcumin, Bisdemethoxycurcumin, Demethoxycurcumin, Tetrahydrocurcumin, Curcuminol, and Ar-curcumene. The DPPH assay and total antioxidant capacity (TAC) were employed to assess antioxidant activity. Anti-inflammatory effects were determined by measuring the inhibition of heat-induced protein denaturation. Molecular docking and molecular dynamics (MD) simulations were performed to evaluate the interactions between curcuminoids and monkeypox virus proteins. Results: The aqueous extract of Discussion: The results demonstrate the multifunctional therapeutic potential of

Indexed as

anti-inflammatory propertiesantioxidant activityCurcuma longacurcuminoidsmolecular dockingmolecular dynamic simulationsMpox virus

Identifiers

PMID39886556
PMCPMC11780592

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.