Evidence map›Paper›PMID 39886526›Full record

ArticleExtracellular vesicle2024

An extracellular vesicle based hypothesis for the genesis of the polycystic kidney diseases.

Marie C Hogan, Christopher J Ward

Abstract read
In one paragraph

Article in Extracellular vesicle, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. AbioRxiv : the preprint server for biology · 2026
    Article
  3. The extracellular matrix genebioRxiv : the preprint server for biology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marie C HoganDivision of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN 55902, USA.
Christopher J WardThe Jared Grantham Kidney Institute at the University of Kansas Medical Center, Department of Nephrology and Hypertension, University of Kansas Medical Center, Kansas City, KS 66160, USA.

Funding

Polycystin Function Resource Development CoreU54DK126126 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI DARREN P. WALLACE · 2020 to 2026
$5.8M
Human-specific Abnormal Alternative Splicing of the Wild-type PKD1 Gene Induces Premature Termination of Polycystin-1R01DK122205 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI WARD, CHRISTOPHER J · 2020 to 2024
$1.7M
Super resolution microscope for the imaging core facilityS10OD023625 · OD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NISHIMUNE, HIROSHI · 2019 to 2019
$987k
NIDDK NIH HHS R01 DK122205NIDDK NIH HHS U54 DK126126NIH HHS S10 OD023625
6 · The paper itself

Abstract

Autosomal dominant polycystic kidney (ADPKD) disease is the commonest genetic cause of kidney failure (affecting 1:800 individuals) and is due to heterozygous germline mutations in either of two genes,

Indexed as

Autosomal dominant polycystic kidney diseaseAutosomal recessive polycystic kidney diseaseExtracellular vesicleFibrocystinPKD1PKD2PKHD1Polycystin-1Polycystin-2Primary cilium

Identifiers

PMID39886526
PMCPMC11781568

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.