ArticleiScience2025
Amputees but not healthy subjects optimally integrate non-spatially matched visuo-tactile stimuli.
Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Stimulation Modalities in Wearable Haptic Systems: Single-Mode Feedback to Multiphysics Actuation.Research (Washington, D.C.) · 2026Review
- Proprioception impacts body perception in healthy aging - Insights from a psychophysical and computational approach.iScience · 2025Article
- Sense of ownership is linked to the speed of visuomotor adaptation in virtual reality but not to generalization, intermanual transfer, or aftereffects.Scientific reports · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our brain combines sensory inputs to create a univocal perception, enhanced when stimuli originate from the same location. Following amputation, distorted body representations may disrupt visuo-tactile integration at the amputated leg. We aim to unveil the principles guiding optimal and cognitive-efficient visuo-tactile integration at both intact and amputated legs. Hence, we designed a VR electro-stimulating platform to assess the functional and cognitive correlates of visuo-tactile integration in two amputees and sixteen healthy subjects performing a 2-alternative forced choice (2AFC) task. We showed that amputees optimally integrate non-spatially matched stimuli at the amputated leg but not the intact leg (tactile cue at the stump/thigh and visual cue under the virtual foot), while healthy controls only integrated spatially matched visuo-tactile stimuli. Optimal integration also reduced 2AFC task reaction times and was confirmed by cognitive EEG-based mental workload reduction. These findings offer insights into multisensory integration processes, opening new perspectives on amputees' brain plasticity.
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