Evidence map›Paper›PMID 39886225›Full record

ArticleChemical & biomedical imaging2025

Lipid Metabolic Heterogeneity during Early Embryogenesis Revealed by Hyper-3D Stimulated Raman Imaging.

Jie Huang, Ling Zhang, Ninghui Shao, Yongqing Zhang, Yuyan Xu, Yihui Zhou, Delong Zhang, Jin Zhang, Hyeon Jeong Lee

Abstract read
In one paragraph

Article in Chemical & biomedical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jie HuangZhejiang Polytechnic Institute, Polytechnic Institute, Zhejiang University, Hangzhou 310058, China.
Ling ZhangLiangzhu Laboratory, Zhejiang University, Hangzhou 311121, China.
Ninghui ShaoCollege of Biomedical Engineering & Instrument Science, Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou 310058, China.
Yongqing ZhangInterdisciplinary Centre for Quantum Information, Zhejiang Province Key Laboratory of Quantum Technology and Device, Department of Physics, Zhejiang University, Hangzhou 310027, China.
Yuyan XuLiangzhu Laboratory, Zhejiang University, Hangzhou 311121, China.
Yihui ZhouCollege of Biomedical Engineering & Instrument Science, Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou 310058, China.
Delong ZhangInterdisciplinary Centre for Quantum Information, Zhejiang Province Key Laboratory of Quantum Technology and Device, Department of Physics, Zhejiang University, Hangzhou 310027, China.ORCID https://orcid.org/0000-0002-9734-3573
Jin ZhangLiangzhu Laboratory, Zhejiang University, Hangzhou 311121, China.
Hyeon Jeong LeeCollege of Biomedical Engineering & Instrument Science, Key Laboratory for Biomedical Engineering of Ministry of Education, Zhejiang University, Hangzhou 310058, China.ORCID https://orcid.org/0000-0002-2417-9338

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studying embryogenesis is fundamental to understanding developmental biology and reproductive medicine. Its process requires precise spatiotemporal regulations in which lipid metabolism plays a crucial role. However, the spatial dynamics of lipid species at the subcellular level remains obscure due to technical limitations. To address this challenge, we developed a hyperspectral 3D imaging and analysis method based on stimulated Raman scattering microscopy (hyper-3D SRS) to quantitatively assess lipid profiles in individual embryos through submicrometer resolution (

Identifiers

PMID39886225
PMCPMC11775849

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.