Evidence map›Paper›PMID 39885904›Full record

ArticlePhysics and imaging in radiation oncology2025

Feasibility and time gain of implementing artificial intelligence-based delineation tools in daily magnetic resonance image-guided adaptive prostate cancer radiotherapy.

Maximilian Lukas Konrad, Carsten Brink, Anders Smedegaard Bertelsen, Ebbe Laugaard Lorenzen, Bahar Celik, Christina Junker Nyborg, Lars Dysager, Tine Schytte, Uffe Bernchou

Abstract read
In one paragraph

Article in Physics and imaging in radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Direct-to-treatment MRI-guided prostate radiotherapy using a generic patient-agnostic reference plan.Technical innovations & patient support in radiation oncology · 2026
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maximilian Lukas KonradDepartment of Clinical Research, University of Southern Denmark, Denmark.
Carsten BrinkDepartment of Clinical Research, University of Southern Denmark, Denmark.
Anders Smedegaard BertelsenLaboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark.
Ebbe Laugaard LorenzenDepartment of Clinical Research, University of Southern Denmark, Denmark.
Bahar CelikLaboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark.
Christina Junker NyborgDepartment of Clinical Research, University of Southern Denmark, Denmark.
Lars DysagerDepartment of Clinical Research, University of Southern Denmark, Denmark.
Tine SchytteDepartment of Clinical Research, University of Southern Denmark, Denmark.
Uffe BernchouDepartment of Clinical Research, University of Southern Denmark, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Purpose: Daily magnetic resonance image (MRI)-guided radiotherapy plan adaptation requires time-consuming manual contour edits of targets and organs at risk in the online workflow. Recent advances in auto-segmentation promise to deliver high-quality delineations within a short time frame. However, the actual time benefit in a clinical setting is unknown. The current study investigated the feasibility and time gain of implementing online artificial intelligence (AI)-based delineations at a 1.5 T MRI-Linac. Materials and methods: Fifteen consecutive prostate cancer patients, treated to 60 Gy in 20 fractions at a 1.5 T MRI-Linac, were included in the study. The first 5 patients (Group 1) were treated using the standard contouring workflow for all fractions. The last 10 patients (Group 2) were treated with the standard workflow for fractions 1 up to 3 (Group 2 - Standard) and an AI-based workflow for the remaining fractions (Group 2 - AI). AI delineations were delivered using an in-house developed AI inference service and an in-house trained nnU-Net. Results: The AI-based workflow reduced delineation time from 9.8 to 5.3 min. The variance in delineation time seemed to increase during the treatment course for Group 1, while the delineation time for the AI-based workflow was constant (Group 2 - AI). Fewer occurrences of readaptation due to target movement occurred with the AI-based workflow. Conclusion: Implementing an AI-based workflow at the 1.5 T MRI-Linac is feasible and reduces the delineation time. Lower variance in delineation duration supports a better ability to plan daily treatment schedules and avoids delays.

Indexed as

AIAuto-segmentationClinical implementationDeep learningMRIMR-LinacProspective paired studyTreatment planning

Identifiers

PMID39885904
PMCPMC11780162

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.