Trial reportJournal of orthopaedic surgery and research2025
The effects of contralateral limb cross-education training on post-surgical rehabilitation outcomes in patients with anterior cruciate ligament reconstruction: a randomized controlled trial.
Trial report in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cross-Education Effect on Force Production Capacity After Unilateral Resistance Training in Clinical Populations: A Systematic Review with Meta-analysis.Sports medicine (Auckland, N.Z.) · 2026Pooled it
- Effects of contralateral knee functional training on knee function, pain, kinesiophobia, plantar load distribution, and stance-phase parameters after anterior cruciate ligament reconstruction: a single-blind, randomised controlled trial.BMC musculoskeletal disorders · 2026Trial
- Effectiveness of exercise prehabilitation before anterior cruciate ligament reconstruction on functional outcomes - a single-blinded randomized controlled trial.Scientific reports · 2026Trial
- Cross-education after forearm fracture: a randomised controlled trial.Irish journal of medical science · 2026Trial
- Effectiveness of the Addition of a Cross-Education, Mirror Therapy, and Virtual Reality Exercises in Patients with Anterior Cruciate Ligament Reconstruction: The CROSSMIRV Trial Protocol.Journal of clinical medicine · 2026Article
- Cross-education via contralateral-limb balance training improves gait speed and sagittal-plane knee motion after anterior cruciate ligament reconstruction: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2026Article
- Kinesiophobia and knee biomechanical characteristics in patients with postoperative tibial plateau fractures across body mass index categories: a cross-sectional mediation analysis.Journal of orthopaedic surgery and research · 2026Article
- Advances in Gait Alterations and Rehabilitation After Anterior Cruciate Ligament Reconstruction: Biomechanics and Emerging Technologies.Orthopaedic surgery · 2026Review
- Comparison of gait characteristics at different postoperative phases following anterior cruciate ligament reconstruction.BMC sports science, medicine & rehabilitation · 2026Article
- Reproducibility of Cycling Kinetics on an Ergometer Designed to Quantify Asymmetry.Sensors (Basel, Switzerland) · 2026Article
- Postural control characteristics as reflected by center of pressure measurements in anterior cruciate ligament reconstruction patients at varying post-operative stages: a cross-sectional comparative study.Journal of orthopaedic surgery and research · 2026Article
- Evolution of pre- and post-operative balance characteristics in patients undergoing anterior cruciate ligament reconstruction: implications for rehabilitation.Frontiers in bioengineering and biotechnology · 2026Article
- The influence of altered lower-limb muscle strength on dynamic plantar pressure distribution in participants who underwent anterior cruciate ligament reconstruction.Frontiers in sports and active living · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveThis study examines whether cross-education training of the healthy limb promotes cross-transfer through central nervous system stimulation, enhancing the function, kinematic parameters, dynamic balance, and plantar pressure of the affected knee joint in patients recovering from postoperative anterior cruciate ligament reconstruction (ACLR).
methodsForty anterior cruciate ligament reconstruction (ACLR) patients, 5-6 weeks postoperatively, were included and randomly assigned to either an experimental group (n = 20) or a control group (n = 20). The experimental group participated in six weeks of cross-education (CE) training in addition to conventional rehabilitation, while the control group received only conventional rehabilitation. Assessment outcomes included knee function (Lysholm score, joint mobility, and surface electromyographic characteristics of the rectus femoris muscle), kinematic parameters (stride length, stride speed, and stride width), dynamic balance (gait line length, single-support line length, and medial-lateral displacements), and plantar pressure (forefoot, midfoot, and hindfoot pressures). The effect of CE training on postoperative ACLR rehabilitation was comprehensively assessed by comparing the pre- and post-intervention changes within each group and the differences between the groups.
resultsBefore the intervention, no statistically significant differences were observed between the two groups across all measured parameters (P > 0.05). Following the intervention, significant improvements in knee function, kinematic parameters, balance function, and plantar pressure were observed in both groups, with the experimental group showing significantly more significant improvements (P < 0.05). The Lysholm score, range of motion (ROM), and surface electromyographic activity of the rectus femoris muscle were significantly higher in the experimental group compared to the control group (P < 0.01). Among kinematic parameters, the experimental group demonstrated a significant increase in stride length and reduced stride width, whereas differences in stride speed were not statistically significant (P > 0.05). Regarding balance function, the experimental group exhibited significantly longer gait and single-support line lengths, significantly reducing medial-lateral displacement (P < 0.05). Analysis of plantar pressure revealed significant improvements in forefoot and hindfoot pressures in the experimental group, with a particularly notable increase in hindfoot pressure (P < 0.05). However, changes in midfoot pressure were not statistically significant (P > 0.05).
conclusionCE training markedly enhanced knee function, kinematic metrics, dynamic stability, and plantar pressure in postoperative ACLR patients providing initial evidence for the prospective utilization of CE theory in rehabilitation. Nonetheless, the fundamental mechanics of its effects remain ambiguous, and variables such as individual differences and neuromuscular adaptation processes may affect training results. Future studies should examine its long-term impacts and uncover potential neuromuscular pathways to establish a solid scientific basis for improving postoperative rehabilitation procedures.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.