Evidence map›Paper›PMID 39885535›Full record

Trial reportJournal of orthopaedic surgery and research2025

The effects of contralateral limb cross-education training on post-surgical rehabilitation outcomes in patients with anterior cruciate ligament reconstruction: a randomized controlled trial.

Chao Liu, ShiJia Li, JianPing Li, HongHao Zhang, GuQiang Li, XiangZhan Jiang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chao Liu1Department of Special Education and Rehabilitation, Binzhou Medical University, Yantai City, Shandong Province, China.
ShiJia Li1Department of Special Education and Rehabilitation, Binzhou Medical University, Yantai City, Shandong Province, China.
JianPing Li1Department of Special Education and Rehabilitation, Binzhou Medical University, Yantai City, Shandong Province, China.
HongHao Zhang1Department of Special Education and Rehabilitation, Binzhou Medical University, Yantai City, Shandong Province, China.
GuQiang Li1Department of Special Education and Rehabilitation, Binzhou Medical University, Yantai City, Shandong Province, China. lgq100@bzmc.edu.cn.
XiangZhan Jiang1Department of Special Education and Rehabilitation, Binzhou Medical University, Yantai City, Shandong Province, China. xzjiang@bzmc.edu.cn.

Funding

2023 Higher Education Science Research Plan Project of China Association of Higher Education 23ZYJ0228Chinese Association of Rehabilitation Medicine KFKT-2023-026General Project of Shandong Province Undergraduate Teaching Reform Research in 2021 M2021213Industry-University Cooperative Education Project of the Ministry of Education in Shandong Province 202102079007the Scientific Foundation of Binzhou Medical University No. 50012304488
6 · The paper itself

Abstract

objectiveThis study examines whether cross-education training of the healthy limb promotes cross-transfer through central nervous system stimulation, enhancing the function, kinematic parameters, dynamic balance, and plantar pressure of the affected knee joint in patients recovering from postoperative anterior cruciate ligament reconstruction (ACLR).

methodsForty anterior cruciate ligament reconstruction (ACLR) patients, 5-6 weeks postoperatively, were included and randomly assigned to either an experimental group (n = 20) or a control group (n = 20). The experimental group participated in six weeks of cross-education (CE) training in addition to conventional rehabilitation, while the control group received only conventional rehabilitation. Assessment outcomes included knee function (Lysholm score, joint mobility, and surface electromyographic characteristics of the rectus femoris muscle), kinematic parameters (stride length, stride speed, and stride width), dynamic balance (gait line length, single-support line length, and medial-lateral displacements), and plantar pressure (forefoot, midfoot, and hindfoot pressures). The effect of CE training on postoperative ACLR rehabilitation was comprehensively assessed by comparing the pre- and post-intervention changes within each group and the differences between the groups.

resultsBefore the intervention, no statistically significant differences were observed between the two groups across all measured parameters (P > 0.05). Following the intervention, significant improvements in knee function, kinematic parameters, balance function, and plantar pressure were observed in both groups, with the experimental group showing significantly more significant improvements (P < 0.05). The Lysholm score, range of motion (ROM), and surface electromyographic activity of the rectus femoris muscle were significantly higher in the experimental group compared to the control group (P < 0.01). Among kinematic parameters, the experimental group demonstrated a significant increase in stride length and reduced stride width, whereas differences in stride speed were not statistically significant (P > 0.05). Regarding balance function, the experimental group exhibited significantly longer gait and single-support line lengths, significantly reducing medial-lateral displacement (P < 0.05). Analysis of plantar pressure revealed significant improvements in forefoot and hindfoot pressures in the experimental group, with a particularly notable increase in hindfoot pressure (P < 0.05). However, changes in midfoot pressure were not statistically significant (P > 0.05).

conclusionCE training markedly enhanced knee function, kinematic metrics, dynamic stability, and plantar pressure in postoperative ACLR patients providing initial evidence for the prospective utilization of CE theory in rehabilitation. Nonetheless, the fundamental mechanics of its effects remain ambiguous, and variables such as individual differences and neuromuscular adaptation processes may affect training results. Future studies should examine its long-term impacts and uncover potential neuromuscular pathways to establish a solid scientific basis for improving postoperative rehabilitation procedures.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionExercise TherapyPatient Education as TopicPostoperative CareAdultBiomechanical PhenomenaFemaleHumansKnee JointMalePostural BalanceTreatment OutcomeYoung AdultAnterior cruciate ligament graft surgeryCross-transferDynamic stabilityKinematic metricsKnee functionPlantar pressure

Identifiers

PMID39885535
PMCPMC11781057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.