Evidence map›Paper›PMID 39885454›Full record

SynthesisBMC pregnancy and childbirth2025

Exploring the influence of pregnancy on cognitive function in women: a systematic review.

Jana Younis, Malak Bleibel, Jad El Masri, Ali Ismail, Linda Abou-Abbas

Abstract readSystematic Review
In one paragraph

Synthesis in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. The influence of sex on cognition in psychosis.Schizophrenia research. Cognition · 2026
    Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Workplace Discrimination Against Pregnant and Postpartum Employees: Links to Well-Being.International journal of environmental research and public health · 2025
    Review
  9. A Call to Integrate Measures of Environmental Context into Research on Maternal Brain Health.International journal of environmental research and public health · 2025
    Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jana YounisNeuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.
Malak BleibelNeuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.
Jad El MasriNeuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.ORCID http://orcid.org/0000-0001-6991-2508
Ali IsmailNeuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon.ORCID http://orcid.org/0000-0001-5602-3883
Linda Abou-AbbasNeuroscience Research Center, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon. l.abouabbas@ul.edu.lb.ORCID http://orcid.org/0000-0001-9185-3831

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnancy has been increasingly recognized for its potential impact on cognitive function influenced significantly by hormonal fluctuations such as estrogen and progesterone. However, the findings from research in this area remain debated, often varying with individual factors and pregnancy trimesters.

objectiveThis study aims to systematically review existing literature and empirical research to better understand the phenomenon known as "pregnancy brain" and its association with cognitive change.

methodsWe conducted a systematic review of peer-reviewed English language articles sourced from Medline, Cochrane Library, and PubMed. Using search terms (pregnancy OR pregnant) AND (cognit* OR memory OR cognitive function*), we identified relevant articles published from the inception of these databases to July 2023. Due to the diverse outcomes in identified studies, a meta-analysis was not feasible, and therefore, a narrative synthesis was conducted to summarize findings.

resultsScreening 3892 studies yielded 31 that met inclusion criteria, encompassing 1596 pregnant women and 1450 non-pregnant controls. Notably, seven studies originated from Australia, of which four were rated as low quality. The aggregated findings suggest that pregnancy modestly affects verbal memory and attention compared to non-pregnant controls, with indications that this decline persists postnatally.

conclusionFuture efforts should prioritize uncovering the underlying mechanisms driving these cognitive changes during pregnancy and consider developing targeted interventions. Such initiatives aim to mitigate potential impacts on maternal well-being, advocating for comprehensive support systems tailored to pregnant individuals navigating cognitive shifts during this transformative period.

Indexed as

CognitionAttentionFemaleHumansMemoryPregnancyAttentionCognitive functionMemoryPregnancySystematic reviewWomen

Identifiers

PMID39885454
PMCPMC11780924

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.