ArticleBMC pregnancy and childbirth2025
Impact of maternal age on birth weight-related adverse outcomes in newborns: a retrospective study in south-central China.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Prevalence and factors associated with coexisting forms of malnutrition among Malaysian children in the SEANUTS II Study.Scientific reports · 2026Article
- Assessing the impact of China's universal two-child policy on infant health: evidence from a quasi-experimental study.European journal of public health · 2026Article
- Association of grand multiparity with adverse birth outcomes and sociodemographic characteristics: an analysis of nationwide birth data in Japan.Reproductive health · 2025Article
- Oral hygiene status, oral health-related behaviors, sleep, body mass index and dental caries prevalence of a sample aged five from Southwest China: a cross-sectional survey.BMC public health · 2025Article
- Recent Status of Low-Birth-Weight Infants in Japan.Cureus · 2025Article
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5 authors.
Funding
Abstract
backgroundBirth weight is a critical indicator for assessing fetal development and newborn health status. This study aimed to examine both linear and nonlinear associations between maternal age and birth weight and their related adverse outcomes.
methods15,923 delivery data from 2018 to 2021 for pregnant women from the Changsha Maternal and Child Health Care Hospital were reviewed by a retrospective study. Basic information and infant birth weight were retrieved from the Medical Birth Registry. Multivariable regression models and the restricted cubic splines (RCS) analysis were used to identify the associations between maternal age and birth weight and its related adverse outcomes.
resultsThe ages of pregnant women trended upward from 2018 to 2021. Maternal age had a nonlinear association with birth weight (P for nonlinear = 0.028). Gestational weeks had a masking effect on the association between maternal age and birth weight, with an effect value of -7.368. A nonlinear association was found between maternal age and macrosomia (P for nonlinear = 0.009). Maternal age increased the risk for large for gestational age (LGA) (OR = 1.016, 95% CI: 1.006-1.027, P = 0.002) and preterm birth (OR = 1.028, 95% CI: 1.008-1.049, P = 0.005).
conclusionsThis retrospective study from south-central China indicates that pregnant women are getting older and maternal age is nonlinearly associated with birth weight, while this association is masked by gestational weeks. Advanced maternal age increases the risk for heavier birth weight-related adverse outcomes.
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