Evidence map›Paper›PMID 39885254›Full record

ArticleScientific reports2025

Renal dysfunction contributes to deteriorated survival outcomes in patients with upper and lower gastrointestinal bleeding: insights from a cohort study of 1160 cases.

Orsolya Anna Simon, Levente Frim, Nelli Farkas, Zoltán Sipos, Nóra Vörhendi, Eszter Boros, Dániel Pálinkás, Brigitta Teutsch, Patrícia Kalló, Vivien Vass and 5 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Orsolya Anna SimonFirst Department of Medicine, Medical School, University of Pécs, Ifjúság Útja 13, 7624, Pécs, Hungary. simon.orsolya@pte.hu.ORCID 0000-0001-7265-9427
Levente FrimFirst Department of Medicine, Medical School, University of Pécs, Ifjúság Útja 13, 7624, Pécs, Hungary.ORCID 0000-0003-0097-6663
Nelli FarkasInstitute of Bioanalysis, Medical School, University of Pécs, Pécs, Hungary.ORCID 0000-0002-5349-6527
Zoltán SiposInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.ORCID 0000-0001-7845-8116
Nóra VörhendiInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.ORCID 0000-0001-6972-1154
Eszter BorosInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.ORCID 0000-0002-7831-163X
Dániel PálinkásCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.ORCID 0000-0001-5578-1754
Brigitta TeutschInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.ORCID 0000-0002-9530-7886
Patrícia KallóInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.
Vivien VassInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.ORCID 0009-0004-6099-426X
Andrea SzentesiInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.ORCID 0000-0003-2097-6927
Roland HágendornFirst Department of Medicine, Medical School, University of Pécs, Ifjúság Útja 13, 7624, Pécs, Hungary.ORCID 0000-0002-9984-2309
Péter HegyiInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.ORCID 0000-0003-0399-7259
Bálint ErőssInstitute for Translational Medicine, Medical School, University of Pécs, Pécs, Hungary.ORCID 0000-0003-3658-8427
Imre SzabóFirst Department of Medicine, Medical School, University of Pécs, Ifjúság Útja 13, 7624, Pécs, Hungary.ORCID 0000-0002-3091-5864

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both acute kidney injury and chronic kidney disease are risk factors for many outcomes of gastrointestinal bleeding (GIB). These are associated with higher mortality, longer hospitalisation, and greater need for transfusion in case of overt GIB. Our study aimed to further evaluate the role of kidney function in several clinical outcomes of GIB patients. The Hungarian Gastrointestinal Bleeding Registry collected data on all-cause GIB between 2019 and 2022. A multi-level data-validation system provided high-quality data, which was retrospectively analysed. Numerous primary (in-hospital mortality, discharge, need for endoscopic intervention, in-hospital rebleeding, length of hospitalisation, need for emergency surgery, need for endoscopic examination and need for intensive care unit) and secondary (detection of Helicobacter pylori (H. pylori), recognition of cancer as the source of bleeding, need for any kind of transfusion or clotting factor, anticoagulation therapy) outcomes were observed. Descriptive statistical tools were used to summarize our data. Among others, estimated glomerular filtration rate (eGFR) (ml/min/1.73 m

Indexed as

Acute Kidney InjuryGastrointestinal HemorrhageRenal Insufficiency, ChronicAgedAged, 80 and overCohort StudiesFemaleGlomerular Filtration RateHospital MortalityHumansMaleMiddle AgedRegistriesRetrospective StudiesRisk FactorsGastrointestinal bleedingKidney functionMortalitySurvivalTransfusion

Identifiers

PMID39885254
PMCPMC11782606

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.