Evidence map›Paper›PMID 39885248›Full record

ArticleScientific reports2025

Deep learning-based malaria parasite detection: convolutional neural networks model for accurate species identification of Plasmodium falciparum and Plasmodium vivax.

Diego A Ramos-Briceño, Alessandro Flammia-D'Aleo, Gerardo Fernández-López, Fhabián S Carrión-Nessi, David A Forero-Peña

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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diego A Ramos-Briceño *School of Systems Engineering, Faculty of Engineering, Universidad Metropolitana de Caracas, Caracas, Venezuela.
Alessandro Flammia-D'Aleo *School of Systems Engineering, Faculty of Engineering, Universidad Metropolitana de Caracas, Caracas, Venezuela.
Gerardo Fernández-LópezDepartment of Electronics and Circuits, Faculty of Engineering, Universidad Simón Bolívar, Caracas, Venezuela.
Fhabián S Carrión-NessiBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolívar, Venezuela. fhabiancarrion@gmail.com.
David A Forero-PeñaBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolívar, Venezuela. vacter.cv@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate malaria diagnosis with precise identification of Plasmodium species is crucial for an effective treatment. While microscopy is still the gold standard in malaria diagnosis, it relies heavily on trained personnel. Artificial intelligence (AI) advances, particularly convolutional neural networks (CNNs), have significantly improved diagnostic capabilities and accuracy by enabling the automated analysis of medical images. Previous models efficiently detected malaria parasites in red blood cells but had difficulty differentiating between species. We propose a CNN-based model for classifying cells infected by P. falciparum, P. vivax, and uninfected white blood cells from thick blood smears. Our best-performing model utilizes a seven-channel input and correctly predicted 12,876 out of 12,954 cases. We also generated a cross-validation confusion matrix that showed the results of five iterations, achieving 63,654 out of 64,126 true predictions. The model's accuracy reached 99.51%, a precision of 99.26%, a recall of 99.26%, a specificity of 99.63%, an F1 score of 99.26%, and a loss of 2.3%. We are now developing a system based on real-world quality images to create a comprehensive detection tool for remote regions where trained microscopists are unavailable.

Indexed as

Deep LearningMalaria, FalciparumMalaria, VivaxNeural Networks, ComputerPlasmodium falciparumPlasmodium vivaxConvolutional Neural NetworksHumansArtificial intelligenceDeep learningMalariaMedical image processingNeural network modelPlasmodium infection

Identifiers

PMID39885248
PMCPMC11782605

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.