Evidence map›Paper›PMID 39885195›Full record

ArticleScientific reports2025

A study on the effect of blue light on kidney stone formation in rats via the brain-kidney axis.

Dao-Cheng Fang, Yuan-Yuan Hu, Chao Wang, Jie Fan, Hui Wen

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dao-Cheng FangDepartment of Urology, Songjiang hospital affiliated to Shanghai jiaotong university school of medicine, Shanghai, China.
Yuan-Yuan HuDepartment of General Practice, Songjiang hospital affiliated to Shanghai jiaotong university school of medicine, Shanghai, China.
Chao WangDepartment of Urology, Songjiang hospital affiliated to Shanghai jiaotong university school of medicine, Shanghai, China.
Jie FanDepartment of Urology, School of Medicine, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai, China. jief67@sina.com.
Hui WenDepartment of Urology, Songjiang hospital affiliated to Shanghai jiaotong university school of medicine, Shanghai, China. whsimon2000@aliyun.com.

Funding

Shanghai Songjiang District Science and Technology Research Project No. 2023SJKJGG84
6 · The paper itself

Abstract

Kidney stones, a common urological disease, may involve the brain-kidney axis in their formation, though the specific mechanism remains unclear. This study aimed to investigate the effects of blue light on relevant metabolic indicators and oxidative stress status in rats with kidney stones through the brain-kidney axis. A rat model of kidney stones was established by administering 1% ethylene glycol and 2% ammonium chloride. Subsequently, blue light intervention was applied, and the outcomes were compared with those of a control group of normal rats. Our findings revealed that rats with kidney stones receiving blue light intervention exhibited significantly increased levels of antidiuretic hormone, intensified oxidative stress response, and augmented stone formation compared to kidney stone rats without blue light intervention. However, in normal rats, blue light intervention did not cause significant changes in these indicators. In summary, this study indicates that under pathological conditions, blue light may promote the secretion of antidiuretic hormone in serum and enhance oxidative stress response in renal tissues by affecting the brain-kidney axis, thereby accelerating the formation of kidney stones in rats.

Indexed as

BrainKidneyKidney CalculiLightAnimalsBlue LightDisease Models, AnimalMaleOxidative StressRatsRats, Sprague-DawleyBlue lightBrain-kidney axisKidney stonesOxidative stress

Identifiers

PMID39885195
PMCPMC11782571

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.