Evidence map›Paper›PMID 39885029›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Isolation and Identification of Coumarins from Citrus latifolia Leaves Using Advanced Chromatographic Techniques.

Hocelayne Paulino Fernandes, Luis Francisco Salomé-Abarca

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Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hocelayne Paulino FernandesNatural Products Laboratory, Institute of Biology, Leiden University, BE, Leiden, The Netherlands. h.paulino.fernandes@biology.leidenuniv.nl.ORCID 0000-0002-2195-2604
Luis Francisco Salomé-AbarcaLaborotorio de Química de Products Naturales, Departmento de Biotecnologia y Bioquímica, Centro de Investigatión y de Estudios Avanzados de IPN, Guanajuato, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coumarins are a class of natural compounds that exhibit a wide range of biological activities, which include anticoagulant, anti-inflammatory, anticancer, and antimicrobial effects. This class of compounds has drawn considerable interest in recent years. The exploration of such properties contributes to our understanding of the potential of coumarins as valuable agents in various clinical applications. Thus, several scientific articles providing a comprehensive exploration of the isolation of coumarins from various plant species have been published. Therefore, this chapter presents an already tested protocol that ensures the effective extraction and isolation of different coumarins from leaves of Citrus latifolia, achieved by liquid and planar chromatography. The identification of coumarins is performed by TLC and

Indexed as

CitrusCoumarinsPlant ExtractsPlant LeavesChromatography, Thin LayerCoumarinsPlant ExtractsCitrus latifoliaCoumarinsIsolationMedium-pressure liquid chromatographyNMRStructure elucidationThin-layer chromatography

Identifiers

PMID39885029

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.