Evidence map›Paper›PMID 39885012›Full record

ArticleAIDS and behavior2025

PrEP Disparities Among Transgender Feminine, Transgender Masculine, Nonbinary, and Gender Expansive Youth and Young Adults in the United States.

Anne E Fehrenbacher, Demetria Cain, Joshua A Rusow, Swetha Lakshmanan, Dianna Polanco, Demi Ward, Yara Tapia, Risa P Flynn, Patrick S Sullivan, W Scott Comulada and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Anne E FehrenbacherDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. afehrenb@usc.edu.ORCID http://orcid.org/0000-0002-0880-2660
Demetria CainDepartment of Psychology, Hunter College, City University of New York, New York, NY, USA.ORCID http://orcid.org/0000-0002-9360-9928
Joshua A RusowGeorge Warren Brown School of Social Work, Washington University, St. Louis, MO, USA.ORCID http://orcid.org/0000-0002-5093-5862
Swetha LakshmananAnderson School of Management, University of California, Los Angeles, CA, USA.
Dianna PolancoMedical College of Wisconsin, Milwaukee, WI, USA.
Demi WardDepartment of Musicology and Ethnomusicology, Tulane University, New Orleans, LA, USA.
Yara TapiaDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Risa P FlynnLos Angeles LGBT Center, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-0289-2842
Patrick S SullivanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-7728-0587
W Scott ComuladaDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-1340-6371
Keith J HorvathDepartment of Psychology, San Diego State University, San Diego, CA, USA.ORCID http://orcid.org/0000-0001-7569-2839
Cathy J RebackFriends Research Institute, Inc, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-4375-7452
Dallas T SwendemanDepartment of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0002-4570-6352
Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) CARES Team

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
Project-003U24HD089880 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HUDGENS, MICHAEL G, LAVANGE, LISA · 2016 to 2021
$44.3M
The UNC/Emory Center for Innovative Technology (iTech) across the prevention and care continuumU19HD089881 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HIGHTOW-WEIDMAN, LISA B, SULLIVAN, PATRICK SEAN · 2016 to 2022
$35.8M
Optimizing the HIV Treatment Continuum with a Stepped Care Model for Youth Living with HIVU19HD089886 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FERNANDEZ, MARIA ISABEL, ROTHERAM-BORUS, MARY JANE · 2016 to 2022
$23.4M
University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
Post-doctoral HIV Research Training Program for HIV Combination PreventionT32MH109205 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTHERAM-BORUS, MARY JANE · 2016 to 2020
$2.3M
PrEP Implementation Science with Hard to Reach Populations in IndiaK01TW012173 · FIC · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Anne Elizabeth Fehrenbacher · 2022 to 2026
$911k
Eunice Kennedy Shriver National Institute of Child Health and Human Development U19HD089881Eunice Kennedy Shriver National Institute of Child Health and Human Development U19HD089886Eunice Kennedy Shriver National Institute of Child Health and Human Development U24HD089880FIC NIH HHS D43 TW009343FIC NIH HHS K01 TW012173FIC NIH HHS K01TW012173NICHD NIH HHS U19 HD089881NICHD NIH HHS U19 HD089886NICHD NIH HHS U24 HD089880NIMH NIH HHS P30 MH058107NIMH NIH HHS T32 MH109205NIMH NIH HHS T32MH109205
6 · The paper itself

Abstract

This study assessed disparities in pre-exposure prophylaxis (PrEP) use among transgender and gender expansive youth and young adults (N = 477) between 15 and 24 years old in the CARES (ATN 149) and TechStep (ATN 160) study protocols within the National Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). Structural equation modeling was used to test mediation pathways between gender identity and PrEP uptake among the full sample and stratified by sex assigned at birth. Lifetime PrEP uptake was higher among those assigned male at birth (26%) versus assigned female at birth (9%), explained by greater structural and behavioral risks and perceived need for PrEP, especially among trans women. Among those assigned female at birth, PrEP uptake was higher among trans men (12%) than nonbinary participants (6%). Our findings characterize key structural and behavioral drivers of PrEP use and highlight the need to reduce barriers to healthcare for trans youth, particularly in the South.

Indexed as

Anti-HIV AgentsHealthcare DisparitiesHIV InfectionsPre-Exposure ProphylaxisTransgender PersonsAdolescentFemaleGender IdentityHumansMaleUnited StatesYoung AdultAnti-HIV AgentsAdolescentsDisparitiesHIV preventionPrEPTransgender

Identifiers

PMID39885012
PMCPMC11985685

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.