ArticleProtoplasma2025
Morphological, anatomical, and bioactive properties of Hypericum scabrum L.: effects on diabetes mellitus, Alzheimer's disease, and HDFa fibroblasts and U87-MG cancer cells.
Article in Protoplasma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Influence of black garlic and Hypericum scabrum on growth performance, fecal microbiota, diarrhea, oxidative stress and immune status in pre-weaning calves.Tropical animal health and production · 2026Article
- GK-11: a Novel Cationic Peptide with Antibiofilm Activity against Staphylococcus aureus and Pseudomonas aeruginosa.Probiotics and antimicrobial proteins · 2026Article
- Potential medical applicability of N-β-Ala and N-His dipeptidomimetics against breast cancer: short in vitro and in silico screening.Scientific reports · 2026Article
- Chemical, biological, morphological, and anatomical exploration of Tripleurospermum monticolum Born. (Asteraceae): A promising medicinal plant.Protoplasma · 2026Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus (DM) and cancer are multifactorial diseases with significant health consequences, and their relationship with aging makes them particularly challenging. Epidemiological data suggests that individuals with DM are more susceptible to certain cancers. This study examined the bioactive properties of Hypericum scabrum extracts, including methanol, hexane, and others, focusing on their inhibitory effects on key enzymes associated with DM and neurodegenerative diseases, such as acetylcholinesterase, butyrylcholinesterase, α-amylase, and α-glucosidase. Additionally, the impact of these extracts on human fibroblast (HDFa) and glioblastoma (U87MG) cancer cells was evaluated. The methanol extract was analyzed for elemental composition using ICP-MS, secondary metabolites, and amino acids via LC-MS/MS and underwent morphological and anatomical characterization. The methanol extract demonstrated notable inhibitory activity, with an IC
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.