ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025
MIRD Pamphlet No. 32: A MIRD Recovery Coefficient Model for Resolution Characterization and Shape-Specific Partial-Volume Correction.
Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Dosimetry Analysis ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026Trial
- Influence of increased injected activities up 9.0 GBq [EJNMMI physics · 2026Article
- State-of-the-art and future developments in dosimetry for SSTR- and PSMA-targeting radioligand therapies.Zeitschrift fur medizinische Physik · 2026Review
- Estimation and Correction of the Partial Volume Effect Using Personalized Phantoms of Lymph Node Metastases in Lutetium 177 SPECT/CT Dosimetry.Molecular imaging and biology · 2026Article
- Improved patient models for simulation of clinically realisticEJNMMI physics · 2026Article
- Intersoftware variability in SPECT quality control: A technical note on analytical discrepancies and compliance decisions.Journal of applied clinical medical physics · 2026Article
- Investigation of iterative deconvolution inEJNMMI physics · 2026Article
- Impact of partial volume correction on radiomics reproducibility in theranostic SPECT/CT imaging.Medical physics · 2026Article
- Direct estimation of activity concentration in regional voxels with application toMedical physics · 2026Article
- Critical review of partial volume correction methods in PET and SPECT imaging: benefits, pitfalls, challenges, and future outlook.European journal of nuclear medicine and molecular imaging · 2026Review
- MIRD Pamphlet No. 33: MIRDpvc-A Software Tool for Recovery Coefficient-Based Partial-Volume Correction.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- Extravasation Frequency of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- Article
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Authors and funding
10 authors.
Funding
Abstract
Accurate quantification in emission tomography is essential for internal radiopharmaceutical therapy dosimetry. Mean activity concentration measurements in objects with diameters less than 10 times the full width at half maximum of the imaging system's spatial resolution are significantly affected (>10%) by the partial-volume effect. This study develops a framework for PET and SPECT spatial resolution characterization and proposes 2 MIRD recovery coefficient models-a geometric mean approximation (RECOVER-GM) and an empirical model (RECOVER-EM)-that provide shape-specific partial-volume correction (PVC). The models were validated using simulations and phantom experiments, with a comparative PVC test on ellipsoidal phantoms demonstrating that the RECOVER models significantly reduced error in activity quantification by factors of approximately 1.3-5.7 compared with conventional sphere-based corrections. The proposed recovery coefficient models and PVC methodology provide a robust framework for improved region-based PVC, including corrections for nonspherical tumor volumes. This work is part of the ongoing MIRDsoft.org project that aims to enhance accessibility to advanced dosimetry tools for improved disease characterization, treatment planning, and radiopharmaceutical therapy dosimetry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.