Evidence map›Paper›PMID 39884648›Full record

ArticleContemporary clinical trials2025

A protocol for a wait list control trial of an intervention to improve pain and depressive symptoms among middle-aged and older women living with disabilities.

Janiece L Taylor, Catherine A Clair, Shelbie Atkins, Claire Wang, Ashley Booth, M Carrington Reid, Elaine Wethington, Natalie G Regier

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05619510 (Testing an Intervention to Reduce Pain and Depression Among Older Women With Physical Disabilities), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05619510 naterminatednot on this map

Testing an Intervention to Reduce Pain and Depression Among Older Women With Physical Disabilities

TypeinterventionalSponsorJohns Hopkins UniversityRan2023 to 2026Enrolled9ConditionsPain, Chronic, Depressive Symptoms, Depression, Disability PhysicalArmsPRIME Intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Janiece L TaylorJohns Hopkins School of Nursing, Baltimore, MD, United States of America. Electronic address: jwalke90@jhu.edu.
Catherine A ClairJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
Shelbie AtkinsJohns Hopkins School of Nursing, Baltimore, MD, United States of America.
Claire WangJohns Hopkins School of Nursing, Baltimore, MD, United States of America.
Ashley BoothJohns Hopkins School of Nursing, Baltimore, MD, United States of America; Johns Hopkins School of Medicine, Baltimore, MD, United States of America.
M Carrington ReidDivision of Geriatrics and Palliative Medicine, Weill Cornell Medicine, New York, NY, United States of America.
Elaine WethingtonDepartment of Psychology and Department of Sociology, Cornell University, Ithaca, NY, United States of America.
Natalie G RegierJohns Hopkins School of Nursing, Baltimore, MD, United States of America.

Funding

Pilot CoreP30AG022845 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Manney Carrington Reid · 2003 to 2026
$15.2M
Clinical Research&Epidemiology in Diabetes&EndocrinologyT32DK062707 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI TODD T BROWN, Wendy Lynet Bennett · 2002 to 2026
$7.3M
Reid Aging and Pain Research Training ProgramK24AG053462 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI REID, MANNEY CARRINGTON · 2016 to 2025
$1.8M
NIA NIH HHS K24 AG053462NIA NIH HHS P30 AG022845NIDDK NIH HHS T32 DK062707
6 · The paper itself

Abstract

backgroundWomen aging with disabilities experience higher rates of chronic pain and co-occurring depressive symptoms than women without disabilities and men with and without disabilities. Pain and depression can exacerbate the inability to fulfill social roles and complete activities of daily living among women with disabilities. Although there are existing interventions for both pain and depressive symptoms, few interventions have been developed with women aging with disabilities that address both chronic pain and depressive symptoms. PURPOSE: The aim of this study is to ascertain the acceptability and feasibility of the Women in Pain Reduction & Improved Mood through Empowerment (PRIME) intervention in a sample of middle-aged and older women living with pain, depressive symptoms, and physical disabilities (i.e., mobility disability).

methodsIn this wait-list, randomized controlled trial we will assess the intervention's 1) feasibility by determining recruitment and retention rates; 2) acceptability through qualitative interviews with all enrolled participants; and 3) preliminary efficacy by determining changes in pain and depressive symptoms between immediate intervention and waitlist control participants to estimate effect sizes to inform future research.

conclusionThis intervention has two main components, which have the potential to decrease pain and depressive symptoms and lead to increased quality of life. It is imperative that clinical trials are designed and structured with the partnership and needs of women with disabilities at the center. This trial is registered at clinicaltrials.gov, NCT05619510, 11/09/2022.

Indexed as

Chronic PainDepressionPain ManagementPersons with DisabilitiesActivities of Daily LivingAgedCross-Over StudiesFeasibility StudiesFemaleHumansMiddle AgedRandomized Controlled Trials as TopicWaiting ListsAfrican American WomenDepressionDisabilityPain

Identifiers

PMID39884648
PMCPMC11892009

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.