Evidence map›Paper›PMID 39884317›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2025

Responses of skeletal muscle to mechanical stimuli in female rats following and during muscle disuse atrophy.

Alexander B Sklivas, Zachary R Hettinger, Sarah Rose, Alessandra Mantuano, Amy L Confides, Sandra Rigsby, Frederick F Peelor, Benjamin F Miller, Timothy A Butterfield, Esther E Dupont-Versteegden

Abstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alexander B SklivasDepartment Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.ORCID 0000-0002-8887-4487
Zachary R HettingerAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States.
Sarah RoseCenter for Muscle Biology, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.
Alessandra MantuanoCenter for Muscle Biology, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.
Amy L ConfidesCenter for Muscle Biology, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.
Sandra RigsbyAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States.
Frederick F PeelorAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States.
Benjamin F MillerAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States.ORCID 0000-0003-3283-0685
Timothy A ButterfieldCenter for Muscle Biology, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.ORCID 0000-0002-8787-2148
Esther E Dupont-VersteegdenDepartment Physical Therapy, College of Health Sciences, University of Kentucky, Lexington, Kentucky, United States.ORCID 0000-0001-5576-9659

Funding

Mechanisms underlying anabolic effects of cyclic compressive loading in muscleR01AT009268 · NCCIH · UNIVERSITY OF KENTUCKY · PI BUTTERFIELD, TIMOTHY ALAN, DUPONT-VERSTEEGDEN, ESTHER E · 2017 to 2021
$2.3M
CRR LIGAND ASSAY AND ANALYSIS CORER24HD102061 · NICHD · UNIVERSITY OF VIRGINIA · PI HAISENLEDER, DANIEL J. · 2019 to 2023
$2.2M
HHS | NIH | National Center for Complementary and Integrative Health (OAM) AT009268HHS | NIH | National Center for Complementary and Integrative Health (OAM) AT009268-02S1HHS | NIH | National Center for Complementary and Integrative Health (OAM) AT009268-05S1HHS | NIH | NICHD | Reproductive Scientist Development Program (RSDP) R24HD102061NCCIH NIH HHS R01 AT009268NICHD NIH HHS R24 HD102061
6 · The paper itself

Abstract

The purpose of this study was to investigate the ability of mechanotherapy to enhance recovery or prevent loss of muscle size with disuse in female rats. Female F344/BN rats were assigned to weight bearing (WB), hindlimb suspended (HS) for 14 days with reambulation for 7 days without mechanotherapy or reambulation (RA) with mechanotherapy (RAM) (

Indexed as

Muscle, SkeletalMuscular AtrophyMuscular Disorders, AtrophicAnimalsCollagenFemaleHindlimb SuspensionMuscle Fibers, SkeletalRatsRats, Inbred F344Satellite Cells, Skeletal MuscleWeight-BearingCollagendisuse atrophymassagemechanosensingmuscle regrowthsex differences

Identifiers

PMID39884317
PMCPMC12184423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.