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ArticleInternational journal of surgery case reports2025

Intracholecystic papillary neoplasm: A case report.

Imen Helal, Raja Jouini, Ehsen Ben Brahim, Mona Cherif, Fatma Khanchel, Aschraf Chadli-Debbiche

Abstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Intracholecystic papillary neoplasm in a pediatric patient: a case report.International journal of surgery case reports · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Imen HelalFaculty of Medicine of Tunis, Tunis El Manar University, Djebal Lakhdar Street, 1006 Tunis, Tunisia; Department of Pathology, Habib Thameur Hospital, 1082 Tunis, Tunisia. Electronic address: imen.helal@gmail.com.
Raja JouiniFaculty of Medicine of Tunis, Tunis El Manar University, Djebal Lakhdar Street, 1006 Tunis, Tunisia; Department of Pathology, Habib Thameur Hospital, 1082 Tunis, Tunisia.
Ehsen Ben BrahimFaculty of Medicine of Tunis, Tunis El Manar University, Djebal Lakhdar Street, 1006 Tunis, Tunisia; Department of Pathology, Habib Thameur Hospital, 1082 Tunis, Tunisia.
Mona CherifFaculty of Medicine of Tunis, Tunis El Manar University, Djebal Lakhdar Street, 1006 Tunis, Tunisia; Department of General Surgery, Habib Thameur Hospital, 1082 Tunis, Tunisia.
Fatma KhanchelFaculty of Medicine of Tunis, Tunis El Manar University, Djebal Lakhdar Street, 1006 Tunis, Tunisia; Department of Pathology, Habib Thameur Hospital, 1082 Tunis, Tunisia.
Aschraf Chadli-DebbicheFaculty of Medicine of Tunis, Tunis El Manar University, Djebal Lakhdar Street, 1006 Tunis, Tunisia; Department of Pathology, Habib Thameur Hospital, 1082 Tunis, Tunisia. Electronic address: aschraf.chadli@fmt.utm.tn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and importanceMore needs to be understood concerning the natural progression and visual attributes of intracholecystic papillary neoplasm. Its longevity, especially the rate at which it transitions from benign to malignant growths, remains ambiguous. Consequently, it is imperative to elucidate the intrinsic progression of this precancerous lesion in the gallbladder. CASE PRESENTATION: A 70-year-old North African woman arrived at the emergency department with abdominal pain, anorexia, and weight loss. The patient's physical examination showed favourable results for abdominal pain, nausea, vomiting, and constipation. A CT scan revealed a heterogeneous fundic tissue mass within the gallbladder, which indicated a cholecystectomy due to clinical manifestations and suspicion of a neoplastic disease. The patient underwent a laparoscopic cholecystectomy, and the removed gallbladder was addressed for pathological analysis, revealing an intracholecystic papillary neoplasm. CLINICAL DISCUSSION: Intracholecystic papillary neoplasm (ICPN) is a rare precancerous tumour affecting middle-aged women aged 38 to 83. It is characterized by raised projections of the lining epithelium in the gallbladder cavity, with a prominent mucinous substance. ICPN can be diagnosed using ultrasound, CT scan, and MRI. Treatment usually involves surgical removal of the gallbladder, known as cholecystectomy, and histological analysis to determine the tumour's stage and grade. Early detection is crucial for preventing the progression of ICPN into invasive carcinoma.

conclusionDue to the rarity of ICPN, more data are needed to establish more effective diagnostic procedures and screening criteria. The main objective of reporting this case is to increase awareness of this rare and potentially fatal tumour.

Indexed as

GallbladderIntracholecystic papillary neoplasmLaparoscopic cholecystectomy

Identifiers

PMID39884169
PMCPMC11816216

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.