Evidence map›Paper›PMID 39883844›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Design of a light and Ca

Zinah Hilal Khaleel, Young Hyun No, Nam Hyeong Kim, Do Hyun Bae, Yibing Wu, Suhyeon Kim, Hojae Choi, Da Eun Lee, Se Yun Jeong, Yoon-Joo Ko and 6 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Multistate photoswitches beyond on and off.Nature communications · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Zinah Hilal Khaleel *SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0003-4358-9516
Young Hyun No *SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon 16419, Republic of Korea.
Nam Hyeong Kim *SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon 16419, Republic of Korea.
Do Hyun BaeCenter for Neuroscience Imaging Research, Institute for Basic Science, Suwon 16419, Republic of Korea.
Yibing WuDepartment of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California at San Francisco, San Francisco, CA 94158.
Suhyeon KimSKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0001-8375-2491
Hojae ChoiSKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon 16419, Republic of Korea.
Da Eun LeeSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Se Yun JeongSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.
Yoon-Joo KoLaboratory of Nuclear Magnetic Resonance, National Center for Inter-University Research Facilities, Seoul National University, Seoul 08826, Republic of Korea.
Seong-Gi KimCenter for Neuroscience Imaging Research, Institute for Basic Science, Suwon 16419, Republic of Korea.ORCID 0000-0003-1960-4464
Minah SuhCenter for Neuroscience Imaging Research, Institute for Basic Science, Suwon 16419, Republic of Korea.
Jin-Chul KimNatural Products Research Center, Korea Institute of Science and Technology, Gangneung 25451, Republic of Korea.
William F DeGradoDepartment of Pharmaceutical Chemistry and the Cardiovascular Research Institute, University of California at San Francisco, San Francisco, CA 94158.ORCID 0000-0003-4745-263X
Ki Hyun KimSchool of Pharmacy, Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0002-5285-9138
Yong Ho KimSKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon 16419, Republic of Korea.ORCID 0000-0002-9106-3298

Funding

Deciphering the relationship between structure, dynamics and function in helical bundle proteinsR35GM122603 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WILLIAM DEGRADO · 2017 to 2026
$7.1M
Institute for Basic Science (IBS) IBS-R015-D1Korea Basic Science Institute (KBSI) 2022R1A6C101A751Korea Institute of Science and Technology (KIST) 2E31881-22-032Korea Institute of Science and Technology (KIST) 2E33301Ministry of Trade, Industry and Energy (MOTIE) P0008746National Research Foundation of Korea (NRF) 2019R1A5A2027340National Research Foundation of Korea (NRF) 2021R1A2C2007937National Research Foundation of Korea (NRF) 2021R1A4A1033424National Research Foundation of Korea (NRF) 2023R1A2C3005731National Research Foundation of Korea (NRF) RS-2023-00252972National Research Foundation of Korea (NRF) RS-2023-00302458NIGMS NIH HHS R35 GM122603NSF | BIO | Division of Molecular and Cellular Biosciences (MCB) 2306190NSF | MPS | Division of Chemistry (CHE) 2108660
6 · The paper itself

Abstract

The design of organic-peptide hybrids has the potential to combine our vast knowledge of protein design with small molecule engineering to create hybrid structures with complex functions. Here, we describe the computational design of a photoswitchable Ca

Indexed as

CalciumLightPeptidesBenzopyransBinding SitesCalmodulinIndolesMolecular Dynamics SimulationNitro CompoundsProtein BindingProtein EngineeringBenzopyransCalciumCalmodulinIndolesNitro CompoundsPeptidesspiropyrancalcium(II)-binding motifpeptide–organic hybridphotoswitchableprotein design

Identifiers

PMID39883844
PMCPMC11804555

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.