Evidence map›Paper›PMID 39883841›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Impaired spatial coding of the hippocampus in a dentate gyrus hypoplasia mouse model.

Xiaojing Chen, Ning Cheng, Cheng Wang, James J Knierim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Impaired spatial coding of the hippocampus in a dentate gyrus hypoplasia mouse model.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaojing ChenBrain Research Centre, Department of Neuroscience, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China.ORCID 0000-0003-3522-7486
Ning ChengBrain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
Cheng WangZanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218.
James J KnierimZanvyl Krieger Mind/Brain Institute, Johns Hopkins University, Baltimore, MD 21218.ORCID 0000-0002-1796-2930

Funding

MULTI-SITE ANALYSIS OF HIPPOCAMPAL NEURONAL ENSEMBLESR01NS039456 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JAMES J KNIERIM · 2000 to 2026
$9.1M
Johns Hopkins University Provost's Discovery Award There is no grant numberNational Natural Science Foundation of China 32471085NINDS NIH HHS R01 NS039456STI2030-Major Projects 2022ZD0205500
6 · The paper itself

Abstract

The hippocampal dentate gyrus (DG) is thought to orthogonalize inputs from the entorhinal cortex (pattern separation) and relay this information to the CA3 region. In turn, attractor dynamics in CA3 perform a pattern completion or error correction operation before sending its output to CA1. In a mouse model of congenital hypoplasia of the DG, a deficiency in the

Indexed as

Dentate GyrusAnimalsCA1 Region, HippocampalCalciumDisease Models, AnimalFemaleMaleMiceMutationReceptors, G-Protein-CoupledCalciumGpr177 protein, mouseReceptors, G-Protein-Coupledcalcium imagingdentate gyrusplace cellspatial codingWnt

Identifiers

PMID39883841
PMCPMC11804539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.