Evidence map›Paper›PMID 39883382›Full record

ArticleThe international journal of cardiovascular imaging2025

Myocardial extracellular volume fraction estimations using late enhancement CT in patients with atrial fibrillation: a comparative study with cardiac MR.

Yoshihiko Kagawa, Masafumi Takafuji, Satoshi Fujita, Takanori Kokawa, Tomoyuki Fukuma, Masaki Ishida, Eitaro Fujii, Ryuji Okamoto, Kakuya Kitagawa, Hajime Sakuma and 1 more

Abstract readComparative Study
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In one paragraph

Article in The international journal of cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yoshihiko KagawaDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan.
Masafumi TakafujiDepartment of Radiology, Mie University Graduate School of Medicine, Tsu, Japan.
Satoshi FujitaDepartment of Cardiology, Mie Heart Center, Taki-gun, Mie, Japan.
Takanori KokawaDepartment of Radiology, Mie University Graduate School of Medicine, Tsu, Japan.
Tomoyuki FukumaDepartment of Cardiology, Nabari City Hospital, Nabari, Japan.
Masaki IshidaDepartment of Radiology, Mie University Graduate School of Medicine, Tsu, Japan.
Eitaro FujiiDepartment of Cardiology, Nabari City Hospital, Nabari, Japan.
Ryuji OkamotoDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan.
Kakuya KitagawaDepartment of Advanced Diagnostic Imaging, Mie University Graduate School of Medicine, Tsu, Japan.
Hajime SakumaDepartment of Radiology, Mie University Graduate School of Medicine, Tsu, Japan.
Kaoru DohiDepartment of Cardiology and Nephrology, Mie University Graduate School of Medicine, 2-174, Edobashi, Tsu, Mie, 514-8507, Japan. dohik@clin.medic.mie-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial extracellular volume fraction (ECV) measured via MRI serves as a quantitative indicator of myocardial fibrosis. However, accurate measurement of ECV using MRI in the presence of AF is challenging. Meanwhile, CT could be a promising alternative tool for measuring ECV regardless of sinus rhythm or AF. The purpose of this study was to assess the reliability of estimating ECV using CT in patients with AF by comparing it with MRI-derived ECV. Forty-two patients (n = 42) with AF underwent cardiac CT a median of 12 days before catheter ablation, and cardiac MRI a median of 1 day after catheter ablation. Myocardial ECV measured by CT and MRI was compared. Pre-ablation CT scan was performed in the presence of AF in 25 patients, with the remaining 17 in sinus rhythm (SR). All patients were in SR at the time of MRI post ablation. The average of CT-derived ECVs was 0.277 ± 0.022 and that of MRI-derived ECVs was 0.282 ± 0.019 in patients with AF. The average of CT-derived ECVs was 0.268 ± 0.025 and that of MRI-derived ECVs was 0.278 ± 0.025 in patients with SR at the time of the CT scan. CT and MRI were in good agreement with mean differences of -0.0048 ± 0.027 in AF and - 0.0095 ± 0.0354 in SR. CT-derived ECV in the presence of AF measured before ablation showed good agreement with ECV by MRI in SR after ablation. CT-ECV estimations are reliable and feasible in patients with AF.

Indexed as

Atrial FibrillationContrast MediaMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMultidetector Computed TomographyMyocardiumTomography, X-Ray ComputedAgedCatheter AblationFemaleFibrosisHumansMaleMiddle AgedPredictive Value of TestsReproducibility of ResultsContrast MediaAblationAtrial fibrillationCTExtracellular volume fractionMRIMyocardial fibrosis

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.