Evidence map›Paper›PMID 39883263›Full record

ArticleInfection2025

Comparison of the 2023 ISCVID and ESC Duke clinical criteria for the diagnosis of infective endocarditis among patients with positive blood cultures for new typical microorganisms.

Nicolas Fourré, Virgile Zimmermann, Laurence Senn, Pierre Monney, Georgios Tzimas, Florian Tagini, Piergiorgio Tozzi, Matthias Kirsch, Benoit Guery, Matthaios Papadimitriou-Olivgeris

Abstract readComparative Study
In one paragraph

Article in Infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Newly recognized typical microorganisms in intracardiac prosthetic material-related infective endocarditis: evidence behind their inclusion in the 2023 Duke-ISCVID criteria.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nicolas FourréInfectious Diseases Service, Lausanne University Hospital, Lausanne, Switzerland.
Virgile ZimmermannInfectious Diseases Service, Lausanne University Hospital, Lausanne, Switzerland.
Laurence SennInfectious Diseases Service, Lausanne University Hospital, Lausanne, Switzerland.
Pierre MonneyDepartment of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Georgios TzimasDepartment of Cardiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Florian TaginiInstitute of Microbiology, Lausanne University Hospital, Lausanne, Switzerland.
Piergiorgio TozziDepartment of Cardiac Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Matthias KirschDepartment of Cardiac Surgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Benoit GueryInfectious Diseases Service, Lausanne University Hospital, Lausanne, Switzerland.
Matthaios Papadimitriou-OlivgerisInfectious Diseases Service, Lausanne University Hospital, Lausanne, Switzerland. Matthaios.Papadimitriou-Olivgeris@hopitalvs.ch.ORCID http://orcid.org/0000-0003-0565-5105

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the performance of the Duke clinical criteria of the European Society of Cardiology (ESC; 2015 and 2023 versions) and the 2023 International Society for Cardiovascular Infectious Diseases (ISCVID) in diagnosing infective endocarditis (IE) among patients with bacteraemia/candidaemia by pathogens introduced for the first time as typical microorganisms by ISCVID.

methodsRetrospective study.

settingThis study included adult patients with bacteraemia/candidaemia by such pathogens (coagulase negative staphylococci, Abiotrophia spp., Gemella spp., and Granulicatella spp., Cutibacterium. acnes, Corynebacterium striatum, C. jeikeium, Pseudomonas aeruginosa, Serratia marcescens, non-tuberculous mycobacteria, and Candida spp.) hospitalized at Lausanne University Hospital. Episodes were classified as IE by two expert clinicians.

resultsAmong 463 episodes with bacteraemia/candidaemia by such pathogens, IE was diagnosed in 63 episodes (14%). IE prevalence was 17% among episodes with bacteraemia by Staphylococcus lugdunensis or Abiotrophia spp. No case of IE was identified among Granulicatella spp. and Gemella spp. bacteraemias. Among 113 episodes with intracardiac prosthetic material, IE prevalence was 51% in episodes with bacteraemia by S. epidermidis. Sensitivity for the 2015 Duke-ESC, 2023 Duke-ISCVID, and the 2023 Duke-ESC clinical criteria was calculated at 5%, 57%, and 8%, respectively. More episodes were classified as possible IE by the 2023 Duke-ISCVID (30%) compared to 2015 Duke-ESC (13%) and 2023 Duke-ESC (16%) clinical criteria.

conclusionThe 2023 ISCVID version demonstrated superior sensitivity compared to both 2015 and 2023 Duke-ESC in diagnosing IE caused by new typical microorganisms, compared to the other criteria, albeit an increase in cases being classified as possible IE.

Indexed as

BacteremiaEndocarditisAdultAgedAged, 80 and overBacteriaBlood CultureCandidemiaFemaleHumansMaleMiddle AgedRetrospective StudiesSensitivity and SpecificityBloodstream infectionCandidaemiaDuke criteriaInfective endocarditisPseudomonas aeruginosa

Identifiers

PMID39883263
PMCPMC12316761

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.