ReviewEJNMMI physics2025
A review of state-of-the-art resolution improvement techniques in SPECT imaging.
Review in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Bimodal nanobody agents for cancer imaging and potential intraoperative guidance: a systematic review.Journal of nanobiotechnology · 2026Pooled it
- Acquisition Time-Specific Deep Learning-Guided Image Quality Restoration in Accelerated I-123 DaTSCAN Brain SPECT on a Ring-Shaped CZT-Based Camera.Journal of imaging informatics in medicine · 2026Article
- Clinical application of AI for lung lobe segmentation and functional quantification with SPECT/CT: open-source versus custom models.Scientific reports · 2026Article
- Clinical performance of [European journal of nuclear medicine and molecular imaging · 2026Article
- Pair production tomography enables imaging of MeV-scale gamma-emitting theranostic radionuclides.Research square · 2026Article
- Intersoftware variability in SPECT quality control: A technical note on analytical discrepancies and compliance decisions.Journal of applied clinical medical physics · 2026Article
- Impact of partial volume correction on radiomics reproducibility in theranostic SPECT/CT imaging.Medical physics · 2026Article
- Super-Resolution Reconstruction and Detector Geometric Error Correction for Parallel-Beam Low-Resolution Multi-Detector SPECT: A Proof of Concept.Tomography (Ann Arbor, Mich.) · 2026Article
- Towards practical radiopharmaceutical treatment planning: a review of dosimetry simplification techniques.Theranostics · 2026Review
- Instrumentation Digital Twins in PET and SPECT Imaging: Current Status, Challenges, and Future Directions.Computational and structural biotechnology journal · 2026Review
- Quantitative SPECT/CT: Technique and Clinical Applications.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- Advances in multimodal imaging techniques in nanomedicine: enhancing drug delivery precision.RSC advances · 2025Review
- An update on recent advances in fluorescent materials for fluorescence molecular imaging: a review.RSC advances · 2025Review
- AI in SPECT Imaging: Opportunities and Challenges.Seminars in nuclear medicine · 2025Review
- Recent advances in radionuclide medical imaging techniques.Frontiers in medicine · 2025Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Single photon emission computed tomography (SPECT), a technique capable of capturing functional and molecular information, has been widely adopted in theranostics applications across various fields, including cardiology, neurology, and oncology. The spatial resolution of SPECT imaging is relatively poor, which poses a significant limitation, especially the visualization of small lesions. The main factors affecting the limited spatial resolution of SPECT include projection sampling techniques, hardware and software. Both hardware and software innovations have contributed substantially to improved SPECT imaging quality. The present review provides an overview of state-of-the-art methods for improving spatial resolution in clinical and pre-clinical SPECT systems. It delves into advancements in detector design and modifications, projection sampling techniques, traditional reconstruction algorithm development and optimization, and the emerging role of deep learning. Hardware enhancements can result in SPECT systems that are both lighter and more compact, while also improving spatial resolution. Software innovations can mitigate the costs of hardware modifications. This survey offers a thorough overview of the rapid advancements in resolution enhancement techniques within the field of SPECT, with the objective of identifying the most recent trends. This is anticipated to facilitate further optimization and improvement of clinical systems, enabling the visualization of small lesions in the early stages of tumor detection, thereby enhancing accurate localization and facilitating both diagnostic imaging and radionuclide therapy, ultimately benefiting both clinicians and patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.