ArticleCurrent microbiology2025
Crude Antibiotics and Antifungal Metabolites from Chaetomium globosum Cg6 Suppress Pythium aphanidermatum, Causal Agent of Rhizome Rot of Turmeric.
Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Turmeric is affected by various phytopathogens, which cause huge economic losses to farmers. In the present study, ten isolates of Pythium spp. were isolated from infected turmeric rhizomes and characterized. Besides, forty-five isolates of Chaetomium spp. were isolated and characterized through morphological and molecular methods. Among the 45 isolates, Chaetomium globosum Cg6 exhibited the highest antagonistic activity against Pythium aphanidermatum in vitro. The crude antibiotics produced by C. globosum were characterized and analyzed through TLC, GC/MS, and HPLC. The best isolate, TNAU-Cg6, produced all three antibiotics, viz., chaetoglobosin A, chaetomin, and chaetocin in higher quantity and inhibited the growth of P. aphanidermatum. Liquid formulation of TNAU-Cg6 using modified Glucose Ammonium Nitrate broth supported the highest concentration at the end of 360 days at an optimum dosage of 10 mL l
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