Evidence map›Paper›PMID 39883198›Full record

SynthesisRheumatology international2025

Severity of skin disease strongly correlates with quality of life in people with psoriatic arthritis: a systematic review.

Chiara Pitzalis, Nikki Myall, Mrinalini Dey, Koushan Kouranloo

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Rheumatology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chiara PitzalisPostgraduate Education Centre, East Surrey Hospital, Canada Ave, Redhill, Surrey, RH1 5RH, UK. chiara.pitzalis1@nhs.net.ORCID 0009-0009-0475-2844
Nikki MyallBritish Medical Association, BMA House, Tavistock Square, London, WC1H 9JP, UK.ORCID 0000-0002-2331-7284
Mrinalini DeyCentre for Rheumatic Diseases, Weston Education Centre, Cutcombe Road, London, SE5 9RJ, UK.ORCID 0000-0001-6858-4338
Koushan KouranlooDepartment of Rheumatology, Guy's Hospital, Great Maze Pond, London, SE1 9RT, UK.ORCID 0000-0002-6276-137X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review aims to summarise the association between skin disease and quality of life (QoL) in people with psoriatic arthritis (PsA) and identify areas for future research and management. This review was registered on PROSPERO (CRD42024500994). Databases were searched for articles in English published until 7th January 2025. All study types were included except editorials, conference abstracts and reviews. Data gathered included demographics, treatment, type and severity of skin disease and QoL. Data were analysed using descriptive statistics and summarised using vote-counting. 2338 articles were retrieved with 18 ultimately included (10 cross-sectional; 7 observational cohort; 1 randomised controlled trial). A pooled total of 16,960 patients with PsA were included, with 48.1% male and mean age of 47.6 years (SD 5.78). Tools for assessing psoriasis included the Psoriasis-Area-Severity-Index (PASI, n = 9), Body-Surface-Area (BSA, n = 7), with four using others, and several using a combination. PASI scores ranged from 2.6 (mild) to 9.88 (moderate); BSA was reported as ≥ 3%, 5-10%, or ≥ 10%. QoL was assessed using Dermatology-Life-Quality-Index (DLQI; n = 10); EuroQol-5 Dimension (EQ-5D; n = 3); 36-Item-Short-Form-Survey (SF-36; n = 3); and four studies used other measures. 13 studies reported an association between worse skin disease and poorer QoL in PsA. Three studies reported no association between severity of skin disease and quality of life, while two were undecided. This review highlights that there is an association between dermatological symptoms and QoL in PsA patients, even in milder disease, indicating the importance of multidiscplinary management to facilitate greater QoL and patient outcomes.

Indexed as

Arthritis, PsoriaticQuality of LifeHumansMaleMiddle AgedSeverity of Illness IndexBSADLQIEQ-5DPASIPsoriatic ArthritisQuality of lifeSF-36Sytematic Literature Review

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.