Evidence map›Paper›PMID 39883139›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

One-day dual-tracer examination in neuroendocrine neoplasms: a real advantage of low activity LAFOV PET imaging.

Eduardo Calderón, Lena S Kiefer, Fabian P Schmidt, Wenhong Lan, Andreas S Brendlin, Christian P Reinert, Stephan Singer, Gerald Reischl, Martina Hinterleitner, Helmut Dittmann and 2 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Correlation of [EJNMMI research · 2026
    Article
  3. Large axial field of view PET/CT - Not just a longer PET gantry.Zeitschrift fur medizinische Physik · 2026
    Review
  4. Review
  5. Triple-tracer PET (Scientific reports · 2026
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eduardo CalderónNuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Otfried-Mueller-Str. 14, 72076, Tuebingen, Germany.ORCID 0009-0000-3837-7151
Lena S KieferNuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Otfried-Mueller-Str. 14, 72076, Tuebingen, Germany.
Fabian P SchmidtNuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Otfried-Mueller-Str. 14, 72076, Tuebingen, Germany.
Wenhong LanNuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Otfried-Mueller-Str. 14, 72076, Tuebingen, Germany.
Andreas S BrendlinDiagnostic and Interventional Radiology, University Hospital Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.
Christian P ReinertDiagnostic and Interventional Radiology, University Hospital Tuebingen, Hoppe-Seyler-Str. 3, 72076, Tuebingen, Germany.
Stephan SingerDepartment of Pathology, University Hospital Tuebingen, Liebermeisterstr. 8, 72076, Tuebingen, Germany.
Gerald ReischlWerner Siemens Imaging Center, Preclinical Imaging and Radiopharmacy, Eberhard-Karls University, Roentgenweg 13, 72076, Tuebingen, Germany.
Martina HinterleitnerMedical Oncology and Pneumology (Internal Medicine VIII), University Hospital Tuebingen, Otfried- Mueller-Str. 14, 72076, Tuebingen, Germany.
Helmut DittmannNuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Otfried-Mueller-Str. 14, 72076, Tuebingen, Germany.
Christian la FougèreNuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Otfried-Mueller-Str. 14, 72076, Tuebingen, Germany. christian.lafougere@med.uni-tuebingen.de.ORCID 0000-0001-7519-0417
Nils F TrautweinNuclear Medicine and Clinical Molecular Imaging, University Hospital Tuebingen, Otfried-Mueller-Str. 14, 72076, Tuebingen, Germany.ORCID 0000-0003-3397-6299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSomatostatin receptor (SSTR)-PET is crucial for effective treatment stratification of neuroendocrine neoplasms (NENs). In highly proliferating or poorly differentiated NENs, dual-tracer approaches using additional [

methodsTwenty NEN patients were included in this study. Initially, a low activity [

results[

conclusionLAFOV PET scanners enable a one-day dual-tracer protocol, providing diagnostic image quality while preserving the semi-quantification of two

Indexed as

Neuroendocrine TumorsPositron Emission Tomography Computed TomographyAdultAgedFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedRadioactive TracersRadiopharmaceuticalsReceptors, SomatostatinFluorodeoxyglucose F18Radioactive TracersRadiopharmaceuticalsReceptors, SomatostatinDual-tracer PETLAFOV PET/CTLow activity [18F]FDG PETNeuroendocrine neoplasms

Identifiers

PMID39883139
PMCPMC12119714

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.