Evidence map›Paper›PMID 39883116›Full record

ArticleJournal of the American Heart Association2025

Infection-Related Hospitalization and Incident Heart Failure: The Atherosclerosis Risk in Communities Study.

Rebecca L Molinsky, Amil Shah, Melana Yuzefpolskaya, Bing Yu, Jeffrey R Misialek, Bruno Bohn, David Vock, Richard MacLehose, Barry A Borlaug, Paolo C Colombo and 5 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Rebecca L MolinskyDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0001-9564-0147
Amil ShahCardiovascular Imaging Program, Departments of Medicine and Radiology Brigham and Women's Hospital, Harvard Medical School Boston MA USA.ORCID 0000-0003-1056-4451
Melana YuzefpolskayaDivision of Cardiology, Department of Medicine Columbia University Irving Medical Center New York NY USA.ORCID 0000-0003-4729-8943
Bing YuDepartment of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health University of Texas Health Science Center at Houston Houston TX USA.ORCID 0000-0003-4818-1077
Jeffrey R MisialekDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0003-4583-786X
Bruno BohnDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0001-8961-6968
David VockDivision of Biostatistics, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0002-5459-9579
Richard MacLehoseDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.
Barry A BorlaugDepartment of Cardiovascular Medicine Mayo Clinic College of Medicine and Science Rochester MN USA.ORCID 0000-0001-9375-0596
Paolo C ColomboDivision of Cardiology, Department of Medicine Columbia University Irving Medical Center New York NY USA.ORCID 0000-0003-4977-3285
Chiadi E NdumeleJohns Hopkins Ciccarone Center for the Prevention of Heart Disease Johns Hopkins University School of Medicine Baltimore MD USA.ORCID 0000-0002-1603-282X
Junichi IshigamiDepartment of Epidemiology, Bloomberg School of Public Health Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-6396-3723
Kunihiro MatsushitaDepartment of Epidemiology, Bloomberg School of Public Health Johns Hopkins University Baltimore MD USA.ORCID 0000-0002-7179-718X
Pamela L LutseyDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0002-1572-1340
Ryan T DemmerDivision of Epidemiology and Community Health, School of Public Health University of Minnesota Minneapolis MN USA.ORCID 0000-0003-3429-0379

Funding

Cardiovascular Disease Epidemiology &Prevention TrngT32HL007779 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI PAMELA L. Lutsey, JAMES S PANKOW · 1994 to 2026
$9.3M
Mentoring and Research in Patient-Oriented Cardiovascular PharmacoepidemiologyK24HL159246 · NHLBI · UNIVERSITY OF MINNESOTA · PI PAMELA L. Lutsey · 2021 to 2026
$644k
NHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002CNHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003CNHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004CNHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005CNHLBI NIH HHS HHSN268201700005INHLBI NIH HHS K24 HL159246NHLBI NIH HHS T32 HL007779
6 · The paper itself

Abstract

backgroundThe immune response to infections may become dysregulated and promote myocardial damage contributing to heart failure (HF). We examined the relationship between infection-related hospitalization (IRH) and HF, HF with preserved ejection fraction, and HF with reduced ejection fraction. METHODS AND

resultsWe studied 14 468 adults aged 45 to 64 years in the ARIC (Atherosclerosis Risk in Communities) Study who were HF free at visit 1 (1987-1989). IRH was identified using select

conclusionsIRH was associated with incident HF, HF with reduced ejection fraction, and HF with preserved ejection fraction. IRH might represent a modifiable risk factor for HF pathophysiology.

Indexed as

AtherosclerosisHeart FailureHospitalizationInfectionsFemaleHumansIncidenceMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk AssessmentRisk FactorsStroke VolumeUnited Statesepidemiologyheart failureinfections

Identifiers

PMID39883116
PMCPMC12074748

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.