Evidence map›Paper›PMID 39883092›Full record

ArticleASN neuro2025

A Statistically-Robust Model of the Axomyelin Unit under Normal Physiologic Conditions with Application to Disease States.

Alexander Gow, Jeffrey L Dupree, Douglas L Feinstein, Anne Boullerne

Abstract read
In one paragraph

Article in ASN neuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. MyelinASN neuro · 2026
    Article
  2. Article
  3. Demystifying The MyelinASN neuro · 2025
    Article
  4. Understanding the MyelinASN neuro · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexander GowCenter for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, Michigan, USA.
Jeffrey L DupreeDepartment Anatomy & Neurobiology, Virginia Commonwealth University, Richmond, Virginia, USA.
Douglas L FeinsteinDepartment of Anesthesiology, University of Illinois at Chicago, Chicago, Illinois, USA.
Anne BoullerneDepartment of Anesthesiology, University of Illinois at Chicago, Chicago, Illinois, USA.

Funding

BLRD VA I01 BX002625BLRD VA IK6 BX004852RRD VA I01 RX003955
6 · The paper itself

Abstract

Despite tremendous progress in characterizing the myriad cellular structures in the nervous system, a full appreciation of the interdependent and intricate interactions between these structures is as yet unfulfilled. Indeed, few more so than the interaction between the myelin internode and its ensheathed axon. More than a half-century after the ultrastructural characterization of this axomyelin unit, we lack a reliable understanding of the physiological properties, the significance and consequence of pathobiological processes, and the means to gauge success or failure of interventions designed to mitigate disease. Herein, we highlight shortcomings in the most common statistical procedures used to characterize the myelin

Indexed as

AxonsEncephalomyelitis, Autoimmune, ExperimentalModels, StatisticalMyelin SheathAnimalsMiceEAEexperimental autoimmune encephalomyelitisg ratiohypomyelinationmousemyelinoptic nerveproteolipid protein 1rumpshaker mousestatistical modeling

Identifiers

PMID39883092
PMCPMC11974466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.