Evidence map›Paper›PMID 39883038›Full record

ArticleRNA biology2025

Exploring RNA modifications in infectious non-coding circular RNAs.

Pavel Vopalensky, Anton Škríba, Michela Chiumenti, Lucia Ďuričeková, Anna Šimonová, Ondřej Lukšan, Francesco Di Serio, Beatriz Navarro, Hana Cahova

Abstract read
In one paragraph

Article in RNA biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pavel VopalenskyChemical Biology of Nucleic Acids, Institute of Organic Chemistry and Biochemistry of the CAS, Prague 6, Czechia.ORCID 0000-0002-6171-1557
Anton ŠkríbaChemical Biology of Nucleic Acids, Institute of Organic Chemistry and Biochemistry of the CAS, Prague 6, Czechia.ORCID 0000-0003-1122-1098
Michela ChiumentiInstitute for Sustainable Plant Protection (IPSP), National Research Council of Italy (CNR), Bari, Italy.ORCID 0000-0002-8412-3037
Lucia ĎuričekováChemical Biology of Nucleic Acids, Institute of Organic Chemistry and Biochemistry of the CAS, Prague 6, Czechia.
Anna ŠimonováChemical Biology of Nucleic Acids, Institute of Organic Chemistry and Biochemistry of the CAS, Prague 6, Czechia.
Ondřej LukšanChemical Biology of Nucleic Acids, Institute of Organic Chemistry and Biochemistry of the CAS, Prague 6, Czechia.ORCID 0000-0002-3201-7486
Francesco Di SerioInstitute for Sustainable Plant Protection (IPSP), National Research Council of Italy (CNR), Bari, Italy.ORCID 0000-0003-2822-704X
Beatriz NavarroInstitute for Sustainable Plant Protection (IPSP), National Research Council of Italy (CNR), Bari, Italy.ORCID 0000-0001-8981-1018
Hana CahovaChemical Biology of Nucleic Acids, Institute of Organic Chemistry and Biochemistry of the CAS, Prague 6, Czechia.ORCID 0000-0002-4986-7858

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viroids, small circular non-coding RNAs, act as infectious pathogens in higher plants, demonstrating high stability despite consisting solely of naked RNA. Their dependence of replication on host machinery poses the question of whether RNA modifications play a role in viroid biology. Here, we explore RNA modifications in the avocado sunblotch viroid (ASBVd) and the citrus exocortis viroid (CEVd), representative members of viroids replicating in chloroplasts and the nucleus, respectively, using LC - MS and Oxford Nanopore Technology (ONT) direct RNA sequencing. Although no modification was detected in ASBVd, CEVd contained approximately one m

Indexed as

RNA, CircularRNA Processing, Post-TranscriptionalRNA, ViralViroidsNucleic Acid ConformationPlant DiseasesSequence Analysis, RNAVirus ReplicationRNA, CircularRNA, Viral6-methyladenosinedirect RNA-seqLC-MS, m6A SELECTRNA modificationViroid

Identifiers

PMID39883038
PMCPMC11817525

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.