Evidence map›Paper›PMID 39882743›Full record

ReviewBioanalysis2025

Recent advances in fluorescent gold nanocluster-based bioanalytical analysis and imaging in living cell.

Hanbing Ge, Longhui Zhan, Hao Chen, Ruibo Lv, Yanbo Wen, Mingxiang Chen, Fengniu Lu, Zhiqin Yuan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Bioanalysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hanbing GeCollege of Chemistry, Beijing University of Chemical Technology, Beijing, China.
Longhui ZhanCollege of Chemistry, Beijing University of Chemical Technology, Beijing, China.
Hao ChenCollege of Chemistry, Beijing University of Chemical Technology, Beijing, China.
Ruibo LvCollege of Chemistry, Beijing University of Chemical Technology, Beijing, China.
Yanbo WenCollege of Chemistry, Beijing University of Chemical Technology, Beijing, China.
Mingxiang ChenCollege of Chemistry, Beijing University of Chemical Technology, Beijing, China.
Fengniu LuDepartment of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China.
Zhiqin YuanCollege of Chemistry, Beijing University of Chemical Technology, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasmall and highly fluorescent gold nanoclusters (Au NCs) have been widely used for the construction of sensing and imaging platforms. Specifically, through a combination of surface functionalization and spectral analysis and/or imaging techniques, effective intracellular detection and imaging are realized. In this review, we summarize the recently adopted intracellular analysis and imaging events with Au NCs-based probes. The synthesis of Au NCs is briefly introduced based on stabilizer selection. The principles and applications of fluorometric intracellular detection systems toward different analytes, including small molecules and biomacromolecules, are presented by turnoff, turn-on, and ratiometric tactics. The cell imaging events are summarized based on conventional imaging and high-resolution imaging techniques, respectively. In the end, this review highlights the challenges of intracellular applications with Au NCs.

Indexed as

Fluorescent DyesGoldMetal NanoparticlesOptical ImagingAnimalsHumansFluorescent DyesGoldbioanalysiscell imagingfluorescenceGold nanoclustersintracellular detection

Identifiers

PMID39882743
PMCPMC11853653

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.