Article in Stroke, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
10 authors.
Sanem Aslihan AykanNeurovascular Research Unit, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown (S.A.A., J.H.L., K.S., O.A., D.Y.C., C.A.).ORCID 0000-0001-7335-5556
James Han LaiNeurovascular Research Unit, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown (S.A.A., J.H.L., K.S., O.A., D.Y.C., C.A.).ORCID 0000-0002-8414-0398
Kazutaka SugimotoNeurovascular Research Unit, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown (S.A.A., J.H.L., K.S., O.A., D.Y.C., C.A.).ORCID 0000-0002-7666-2620
Orhan AykanNeurovascular Research Unit, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown (S.A.A., J.H.L., K.S., O.A., D.Y.C., C.A.).
Wai Yee FungHovid Berhad, Ipoh, Malaysia (W.Y.F., D.H.).
David HoHovid Berhad, Ipoh, Malaysia (W.Y.F., D.H.).
Anne JoutelUniversité Paris Cité, Institute of Psychiatry and Neuroscience of (IPNP), INSERM U1266, France (A.J.).ORCID 0000-0003-3963-3860
Sava SakadzicAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown (S.S.).ORCID 0000-0001-6318-1193
David Y ChungNeurovascular Research Unit, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown (S.A.A., J.H.L., K.S., O.A., D.Y.C., C.A.).ORCID 0000-0002-7149-5851
Cenk AyataNeurovascular Research Unit, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown (S.A.A., J.H.L., K.S., O.A., D.Y.C., C.A.).ORCID 0000-0002-3644-6042
Funding
Project 4U19NS123717 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI LINNINGER, ANDREAS A · 2021 to 2025
$13.4M
Investigating the Microvascular Mechanisms of O2 Supply-Demand Mismatch in Small Vessel Disease using Novel High-Resolution Optical ImagingR01NS115401 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI AYATA, CENK, SAKADZIC, SAVA · 2020 to 2024
$3.5M
Brain Stimulation to Improve Neurocognitive Deficits After Subarachnoid HemorrhageR01NS136224 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI David Young Chung · 2024 to 2026
$1.4M
Two-photon Imaging of Oxygen and Blood Flow in Retinal and Cerebral VasculatureR01NS121095 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Sava Sakadzic, Mahnaz Shahidi · 2024 to 2026
backgroundCerebral autosomal-dominant arteriopathy, subcortical infarcts, and leukoencephalopathy is the most prevalent monogenic inherited cause of cerebral small vessel disease. Despite its prevalence, there is currently no proven therapy to prevent or reverse the progression of the disease.
methodsThis study aimed to characterize the functional integrity of long white matter tracts in cerebral autosomal-dominant arteriopathy, subcortical infarcts, and leukoencephalopathy transgenic mice expressing R169C mutant
resultsAt baseline, resting-state interhemispheric and intrahemispheric functional connectivity was significantly lower in Notch3
conclusionsThese data show impaired resting-state functional connectivity and increased foot faults in the Notch3
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Impaired Resting-State Functional Connectivity in Cerebral Autosomal-Dominant Arteriopathy, Subcortical Infarcts, and Leukoencephalopathy Mutant Mice. · full record | OpenQuestion