Evidence map›Paper›PMID 39882395›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2025

Clinical Evaluation of Faricimab in Real-World Diabetic Macular Edema in India- A Multicenter Observational Study.

Debdulal Chakraborty, Sudipta Das, Aniruddha Maiti, Tushar Kanti Sinha, Arnab Das, Jay Sheth, Subhendu Kumar Boral, Soumen Mondal, Krishnendu Nandi

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  16. Real-world outcomes of faricimab in treatment-naïve diabetic macular edema: The Middle East perspective.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Debdulal ChakrabortyDisha Eye Hospitals, Kolkata, India.ORCID 0000-0001-9693-7882
Sudipta DasNethralayam Superspeciality Eye Care, Kolkata, India.
Aniruddha MaitiGlobal Eye Hospitals, Kolkata, India.
Tushar Kanti SinhaDisha Eye Hospitals, Kolkata, India.
Arnab DasDisha Eye Hospitals, Kolkata, India.
Jay ShethDepartment of Retina Services, Shantilal Shanghvi Eye Institute (SSEI), Mumbai, India.ORCID 0000-0002-3590-7759
Subhendu Kumar BoralDisha Eye Hospitals, Kolkata, India.ORCID 0000-0002-8656-8339
Soumen MondalDisha Eye Hospitals, Kolkata, India.
Krishnendu NandiNethralayam Superspeciality Eye Care, Kolkata, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the efficacy of faricimab in real-world clinical settings in India for treating diabetic macular edema (DME) in treatment-naïve and recalcitrant eyes. Patients and Methods: This retrospective study involved 39 eyes (16 treatment-naive and 23 recalcitrant) treated with intravitreal faricimab at four centers in India. Patients received three monthly loading doses followed by a pro-re-nata regimen, with outcomes measured for best-corrected visual acuity (BCVA), central macular thickness (CMT), intraretinal fluid (IRF), subretinal fluid (SRF), and hyperreflective foci (HRF). Results: Significant improvements in BCVA were observed in both treatment-naïve and recalcitrant groups, with greater gains in the naïve group (p<0.001). Overall, BCVA improved from 0.48 logMAR to 0.27 logMAR ( Conclusion: Faricimab treatment resulted in significant improvements in visual acuity and anatomical outcomes in both treatment-naïve and recalcitrant DME eyes, highlighting its potential as a valuable therapeutic option in diverse clinical settings. Further real-world studies are warranted to establish long-term efficacy and safety.

Indexed as

anti VEGFdiabetic macular edemafaricimab

Identifiers

PMID39882395
PMCPMC11776507

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.