Evidence map›Paper›PMID 39882209›Full record

ArticleFrontiers in pediatrics2024

External negative pressure improves lung aeration in near-term rabbit kittens at risk of developing respiratory distress.

C Diedericks, K J Crossley, D Jurkschat, M J Wallace, I M Davies, P J Riddington, A B Te Pas, M J Kitchen, S B Hooper

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Role of the Chest Wall in Newborn Respiratory Function at Birth.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

C DiedericksThe Ritchie Centre, Hudson Institute of Medical Research, Clayton VIC, Australia.
K J CrossleyThe Ritchie Centre, Hudson Institute of Medical Research, Clayton VIC, Australia.
D JurkschatSchool of Physics and Astronomy, Monash University, Clayton VIC, Australia.
M J WallaceThe Ritchie Centre, Hudson Institute of Medical Research, Clayton VIC, Australia.
I M DaviesThe Ritchie Centre, Hudson Institute of Medical Research, Clayton VIC, Australia.
P J RiddingtonThe Ritchie Centre, Hudson Institute of Medical Research, Clayton VIC, Australia.
A B Te PasDivision of Neonatology, Department of Paediatrics, Leiden University Medical Centre, Leiden, Netherlands.
M J KitchenThe Ritchie Centre, Hudson Institute of Medical Research, Clayton VIC, Australia.
S B HooperThe Ritchie Centre, Hudson Institute of Medical Research, Clayton VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: As airway liquid is cleared into lung interstitial tissue after birth, the chest wall must expand to accommodate this liquid and the incoming air. We examined the effect of applying external positive and negative pressures to the chest wall on lung aeration in near-term rabbit kittens at risk of developing respiratory distress. Methods: Rabbit kittens (30 days; term ∼31 days) were randomised into Results: Compared to external atmospheric pressures, external negative pressures expanded the chest (by 2100 ± 43 vs. 1805 ± 59 mm Discussion: External negative pressures increased lung aeration and resulted in a more evenly distributed tidal ventilation immediately after birth in near-term rabbit kittens, whereas external positive pressures reduced lung aeration and compliance.

Indexed as

chest walllung liquidnegative pressure ventilationphase contrast x-rayrespiratory distressswaddling

Identifiers

PMID39882209
PMCPMC11774844

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.