Evidence map›Paper›PMID 39882063›Full record

ArticleRisk management and healthcare policy2025

Association Between GABRG2 and Self-Rating of the Effects of Alcohol in a French Young Adult Sample.

Jenny Skumsnes Moe, Jørgen G Bramness, Ingeborg Bolstad, Jørg Gustav Mørland, Philip Gorwood, Nicolas Ramoz

Abstract read
In one paragraph

Article in Risk management and healthcare policy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jenny Skumsnes MoeResearch Center for Substance Use Disorders and Mental Illness, Innlandet Hospital Trust, Brumunddal, Norway.ORCID 0000-0002-7552-1287
Jørgen G BramnessResearch Center for Substance Use Disorders and Mental Illness, Innlandet Hospital Trust, Brumunddal, Norway.
Ingeborg BolstadResearch Center for Substance Use Disorders and Mental Illness, Innlandet Hospital Trust, Brumunddal, Norway.
Jørg Gustav MørlandDepartment of Alcohol, Tobacco, and Drugs, Norwegian Institute of Public Health, Oslo, Norway.
Philip GorwoodUniversité Paris Cité, Inserm U1266, Institut de Psychiatrie et Neurosciences de Paris (IPNP), Team Vulnerability of Psychiatric and Addictive Disorders, Paris, France.ORCID 0000-0003-1845-3676
Nicolas RamozUniversité Paris Cité, Inserm U1266, Institut de Psychiatrie et Neurosciences de Paris (IPNP), Team Vulnerability of Psychiatric and Addictive Disorders, Paris, France.ORCID 0000-0002-8070-9938

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Alcohol use is a leading risk factor for preventable death, injury, and disease globally. Low sensitivity to the effects of alcohol is influenced by genes and predicts risk for harmful alcohol use and alcohol use disorder (AUD). Alcohol induces effects partly by modulation of gamma-aminobutyric acid receptors type A (GABA Patients and Methods: The study involved 1,409 French university students (34.5% women; mean age 20.3 years). Alcohol sensitivity was measured by the Self-Rating of the Effects of Alcohol Scale (SRE). SRE-scores from initial drinking, regular drinking, and heavy drinking were investigated for correlations with alcohol consumption and for associations with single nucleotide polymorphisms (SNPs) in GABA Results: We replicated correlations between low alcohol sensitivity and high alcohol consumption. We further found an association between the minor allele in rs211014 ( Conclusion: The results from our study suggest that genetic variation in

Indexed as

alcohol useAUDAUDITGABRG2geneticself-rating of the effects of alcohol

Identifiers

PMID39882063
PMCPMC11775821

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.