Evidence map›Paper›PMID 39882056›Full record

ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2024

Point-of-care Ultrasonography in Patients with Hepatorenal Syndrome: A Single Center Observational Study.

Vedaghosh Amara, Anand V Kulkarni, Anand Gupta, Shantan Venishetty, Shanthi R Sripathi, L Siva K Reddy, Arun Kumar Tirumala, Puja Karandikar, Manasa Alla, Sowmya Iyengar and 3 more

Abstract read
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In one paragraph

Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Echoes and Shadows: Predicting Hepatorenal Syndrome Outcomes with Lung Ultrasound and X-rays.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Vedaghosh AmaraDepartment of Critical Care Medicine, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0001-5296-2138
Anand V KulkarniDepartment of Hepatology and Liver Transplantation, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0002-1240-1675
Anand GuptaDepartment of Critical Care Medicine, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0002-7042-0129
Shantan VenishettyDepartment of Hepatology and Liver Transplantation, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0002-1346-1311
Shanthi R SripathiDepartment of Hepatology and Liver Transplantation, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0009-0006-9534-0092
L Siva K ReddyDepartment of Critical Care Medicine, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0003-3316-6579
Arun Kumar TirumalaDepartment of Critical Care Medicine, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0009-0007-5656-5026
Puja KarandikarDepartment of Critical Care Medicine, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0009-0006-2388-4381
Manasa AllaDepartment of Hepatology and Liver Transplantation, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0001-5318-2897
Sowmya IyengarDepartment of Hepatology and Liver Transplantation, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0002-5098-9246
Mithun SharmaDepartment of Hepatology and Liver Transplantation, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0003-4497-9209
Padaki N RaoDepartment of Hepatology and Liver Transplantation, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0003-2983-5768
D Nageshwar ReddyDepartment of Hepatology and Liver Transplantation, AIG Hospitals, Hyderabad, Telangana, India.ORCID https://orcid.org/0000-0001-7540-0496

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim and Background: A combination of terlipressin and albumin is the standard of care for patients with hepatorenal syndrome-acute kidney injury (HRS-AKI). The study aimed to compare the venous congestion using lung ultrasound score (LUS) and radiographic assessment of lung edema (RALE) scores among terlipressin responders and nonresponders and survivors and non-survivors. Materials and methods: In this single-center, prospective, observational study, we included adult patients with HRS-AKI who had received terlipressin and albumin from 28th April 2022 to 16th October 2022. Results: Of the 102 patients included, 74.5% (95%CI: 58.7-93.2) responded to terlipressin. The median dose of terlipressin and albumin was 2 (1-8) mg/day and 100 (40-200) g for a duration of 5 (2-10) days. On Kaplan-Meier analysis, survival was 26.9% of patients in the nonresponder group compared to 61.4% in the responder group ( Conclusion: Lung ultrasound score and chest X-ray can accurately identify venous congestion in the lungs, which is common in patients with advanced liver disease who receive terlipressin and albumin in the intensive care unit (ICU). How to cite this article: Amara V, Kulkarni AV, Gupta A, Venishetty S, Sripathi SR, Reddy LSK,

Indexed as

Acute kidney injuryAcute-on-chronic liver failureCirrhosisLiverPoint-of-care ultrasonographyTerlipressin

Identifiers

PMID39882056
PMCPMC11773588

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.