ArticleCureus2024
Association Between Maternal Periodontitis and Adverse Pregnancy Outcomes: A Cross-Sectional Study at a Maternity Hospital in Kathmandu, Nepal.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Comment on: "Effects of an Oral Health Management Program During Pregnancy: A Randomized Controlled Trial".Oral diseases · 2026Article
- A scientometric analysis of research related to the 'oral-placental axis' hypothesis: current status, hotspots, and future directions.Frontiers in cellular and infection microbiology · 2026Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdverse pregnancy outcomes, including preterm birth and low birth weight, are major global health challenges, leading to millions of newborn deaths each year. Since 1996, periodontitis and related gum diseases have been proposed as potential contributing factors, but research findings remain mixed. Further research is needed to clarify this link.
objectiveThis study aims to assess the status of periodontitis and its association with adverse pregnancy outcomes. METHODOLOGY: A cross-sectional study was conducted among 145 third-trimester mothers attending antenatal care (ANC) checkups at Maternity Hospital in Kathmandu. Data were gathered from medical records, interviews, and oral health screenings using the Community Periodontal Index (CPI) for periodontitis. Birth outcomes were assessed after delivery through medical records, which are considered highly reliable, with established protocols for data entry, consistent documentation, and regular quality control measures ensuring accuracy and consistency across healthcare providers. Ethical approval was obtained from the Nepal Health Research Council (NHRC) (approval no. 423) on September 19, 2023.
resultsPeriodontitis was observed in 53 (36.6%) participants, with a higher prevalence in individuals aged 30 or more (10, 43.5%) and those who were illiterate (4, 50%). Health conditions such as hypertension, diabetes, and urinary tract infections were associated with higher periodontitis rates. However, no significant associations were found between age, education, obstetric history, or health conditions and adverse pregnancy outcomes. Periodontitis showed a significant association with adverse outcomes, with 56.6% of those with periodontitis experiencing adverse outcomes, compared to 32.6% without periodontitis (
conclusionsMaternal periodontitis is significantly associated with adverse pregnancy outcomes, with individuals having periodontitis being 2.69 times more likely to experience such outcomes. These findings highlight the importance of incorporating periodontal care into prenatal healthcare.
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