Evidence map›Paper›PMID 39881764›Full record

ArticleIndian journal of endocrinology and metabolism

The Role of Neck Ultrasonography and Nuclear Imaging in the Diagnosis of Congenital Hypothyroidism.

Soundararajan Sumathy, Sengottaiyan Palanivel, Kethipalli Nagaraju, Chidambaram N B Harisankar, Jeyaraj Ashokraja, Jayachandran Senthilkumar, Palaniyappan Sreenivasan, Subbiah Sridhar

Abstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Soundararajan SumathyDepartment of Radiodiagnosis, Madurai Medical College and Govt. Rajaji Hospital, Madurai, Tamil Nadu, India.
Sengottaiyan PalanivelDepartment of Endocrinology, Madurai Medical College and Govt. Rajaji Hospital, Madurai, Tamil Nadu, India.
Kethipalli NagarajuDepartment of Radiodiagnosis, Madurai Medical College and Govt. Rajaji Hospital, Madurai, Tamil Nadu, India.
Chidambaram N B HarisankarNuclear Physician Meenakshi Mission Hospital and Research Centre, Madurai, Tamil Nadu, India.
Jeyaraj AshokrajaDepartment of Neonatology, Madurai Medical College and Govt. Rajaji Hospital, Madurai, Tamil Nadu, India.
Jayachandran SenthilkumarInstitute of Child Health, Madurai Medical College and Govt. Rajaji Hospital, Madurai, Tamil Nadu, India.
Palaniyappan SreenivasanDepartment of Endocrinology, Madurai Medical College and Govt. Rajaji Hospital, Madurai, Tamil Nadu, India.
Subbiah SridharDepartment of Endocrinology, Madurai Medical College and Govt. Rajaji Hospital, Madurai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Congenital hypothyroidism (CH) is the most common preventable cause of mental retardation, and the two important causes of CH are thyroid dysgenesis and dyshormonogenesis. Thyroid imaging is an integral part of identifying the specific aetiology of CH. We aimed to study the aetiological profile of CH and compare the imaging findings of ultrasonography (USG) and nuclear scintigraphy. Methods: It is a prospective, cross-sectional study conducted over 3 years. The clinical, USG, and technetium-99 Results: Sixty-two CH children were included in the study with an equal male-to-female ratio (1.1:1). There was a significant association between parental consanguinity and CH observed in 35.5% of cases ( Conclusion: Dyshormonogeneis is the more commonly observed etiology of CH as compared to thyroid agenesis in the present study. A combined imaging approach with scintigraphy and USG is needed to delineate the specific etiology of CH. We need long-term Indian data to know the paradigm shift in the etiological pattern of CH as compared to Western studies.

Indexed as

Congenital hypothyroidismdyshormonogenesisIndiamental retardationnewborn thyroid screeningthyroid agenesis

Identifiers

PMID39881764
PMCPMC11774417

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.