Evidence map›Paper›PMID 39881533›Full record

ArticleAnnals of medicine2025

The role of renal dual-energy computed tomography in exploring the gouty kidney: the RENODECT study.

Tristan Pascart, Elie Dauphin, Chio Yokose, Charlotte Jauffret, Aurore Pacaud, Victor Laurent, Vincent Ducoulombier, Hyon K Choi, Jean-François Budzik

Abstract read
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In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tristan PascartDepartment of Rheumatology, Lille Catholic University, Saint-Philibert Hospital, ETHICS laboratory, Lille, EA, France.ORCID 0000-0002-8395-826X
Elie DauphinDepartment of Rheumatology, Lille Catholic University, Saint-Philibert Hospital, ETHICS laboratory, Lille, EA, France.
Chio YokoseMassachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Charlotte JauffretDepartment of Rheumatology, Lille Catholic University, Saint-Philibert Hospital, ETHICS laboratory, Lille, EA, France.
Aurore PacaudDepartment of Rheumatology, Lille Catholic University, Saint-Philibert Hospital, ETHICS laboratory, Lille, EA, France.
Victor LaurentDepartment of Rheumatology, Lille Catholic University, Saint-Philibert Hospital, ETHICS laboratory, Lille, EA, France.
Vincent DucoulombierDepartment of Rheumatology, Lille Catholic University, Saint-Philibert Hospital, ETHICS laboratory, Lille, EA, France.
Hyon K ChoiMassachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Jean-François BudzikDepartment of Medical Imaging, Lille Catholic University, Saint-Philibert Hospital, ETHICS laboratory, Lille, EA, France.

Funding

Personalized Comorbidity-Integrated Gout CareK23AR081425 · NIAMS · MASSACHUSETTS GENERAL HOSPITAL · PI Chio Yokose · 2023 to 2026
$704k
NIAMS NIH HHS K23 AR081425
6 · The paper itself

Abstract

objectiveThe objective of this study was to explore the ability of dual-energy computed tomography (DECT) to detect monosodium urate (MSU) crystal deposits in the kidneys and renal artery walls, and uric acid urolithiasis, in patients with gout and chronic kidney disease (CKD).

methodsPatients with gout and with stage 2-4 CKD were prospectively included in this cross-sectional study. Patients underwent renal, knee and feet DECT scans. Renal DECT scans were read for MSU-coded lesions in the kidneys, renal artery walls, and urinary tract using different post-processing settings. Characteristics of patients with and without DECT-positive lesions were compared, and the DECT parameters of these lesions were measured.

resultsA total of 27/31 patients with had renal DECT scans and were included in the analysis (23/27 men, mean (standard deviation) 73 (9) years old, mean eGFR 45.3 mL/min/1.73 m2 (21.0), volumes of MSU in the knees and feet ranging from 0.11 to 475.0 cm

conclusionDECT is unable to detect genuine monosodium urate crystal deposits in kidneys and renal artery walls, and but can characterize chronic asymptomatic urolithiasis.

Indexed as

GoutKidneyRenal Insufficiency, ChronicTomography, X-Ray ComputedAgedAged, 80 and overCross-Sectional StudiesFemaleHumansMaleMiddle AgedProspective StudiesRenal ArteryUric AcidUric Acidchronic kidney diseasedual-energy computed tomographyGoutmonosodium urateuric acid

Identifiers

PMID39881533
PMCPMC11784065

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.